The limitation of heavy metals in raw materials of traditional Chinese medicine (TCM) is an important issue for the quality control of TCM. The amount of lead (Pb), cadmium (Cd), mercury (Hg), arsenic (As) and copper (Cu) in Aconiti Lateralis Praeparata Radix, Citri Reticulatae Pericarpium Viride, Sophorae Flavescentis Radix, Curcumae Rhizoma, Astragali Radix, Farfarae Flos, Polyporus, Trichosanthis Radix, Gastrodiae Rhizoma, Alpiniae Officinari Rhizoma, Angelicae Pubescentis Radix, Cimicifugae Rhizoma, Fritillariae Cirrhosae Bulbus, Borneolum Syntheticum and Lycii Radicis Cortex were determined by ICP-MS (Inductively coupled plasma-mass spectrometry). The 80(superscript th) percentile of each heavy metal in TCM lied in range of < 0.03-2.38 ppm, < 0.003-1.11 ppm, N.D.-0.05 ppm, < 0.003- 1.06 ppm, and N.D.-16.37 ppm for Pb, Cd, Hg, As and Cu, respectively. For TCM the detection limits of Pb, Cd, Hg, As and Cu were 0.01, 0.001, 0.01, 0.001 and 0.1 ppm, respectively. These survey data could provide limitation assessment of heavy metals in raw materials of TCM as the regulatory authority.
The limitation of heavy metals in raw materials of traditional Chinese medicine (TCM) is an important issue for the quality control of TCM. The amount of lead (Pb), cadmium (Cd), mercury (Hg), arsenic (As) and copper (Cu) in Aconiti Lateralis Praeparata Radix, Citri Reticulatae Pericarpium Viride, Sophorae Flavescentis Radix, Curcumae Rhizoma, Astragali Radix, Farfarae Flos, Polyporus, Trichosanthis Radix, Gastrodiae Rhizoma, Alpiniae Officinari Rhizoma, Angelicae Pubescentis Radix, Cimicifugae Rhizoma, Fritillariae Cirrhosae Bulbus, Borneolum Syntheticum and Lycii Radicis Cortex were determined by ICP-MS (Inductively coupled plasma-mass spectrometry). The 80(superscript th) percentile of each heavy metal in TCM lied in range of < 0.03-2.38 ppm, < 0.003-1.11 ppm, N.D.-0.05 ppm, < 0.003- 1.06 ppm, and N.D.-16.37 ppm for Pb, Cd, Hg, As and Cu, respectively. For TCM the detection limits of Pb, Cd, Hg, As and Cu were 0.01, 0.001, 0.01, 0.001 and 0.1 ppm, respectively. These survey data could provide limitation assessment of heavy metals in raw materials of TCM as the regulatory authority.
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