Magnetic Resonance Imaging Features of Primary Breast Angiosarcomas

Kuang-Fu Chang ； Pei-Ching Huang ； Yun-Chung Cheung

《Journal of Radiological Science》 46卷 (2021/03) Pp. 109-113

https://doi.org/10.6698/JRS.202103_46.0021

摘要

PURPOSE. The purpose of this study was to review the contrast-enhanced magnetic resonance imaging (CE-MRI) of pathologically proven primary breast angiosarcomas (PBAs) from our data from 2009 to 2019. MATERIALS AND METHODS. We reviewed the CE-MRI features of PBA including tumor size, margin, intensity, enhancement pattern, skin invasion, and intratumoral associated findings with the consensus of two radiologists. RESULTS. A total of 5 PBA patients (mean age: 36.6 years) (mean diameter: 10.5 cm; range: 5.4-19.0 cm) were enrolled for analysis, two of which were associated with pregnancy. All the PBAs were large, manifested as rapidly enlarged breasts or masses, and featured irregular (4 cases) or circumscribed (1 case) outlines with skin invasion (2 cases). All showed hypointensity on T1-weighted images and inhomogeneous hyperintensity on T2-weighted short-time inversion recovery on non-contrast MRI, and all were inhomogeneously enhanced with type 1 (2 cases) or type 3 (3 cases) kinetic curves. Intratumoral features revealed serpentine tubular defects and hematomas in 4 and 3 cases, respectively. CONCLUSION. PBAs clinically manifest as rapidly enlarged breasts or masses. CE-MRI can display the morphological features of irregular outlines and inhomogeneous enhancement with either intratumoral hematoma or serpentine defects that facilitate the differential diagnosis.

關鍵字

breast ； breast neoplasm ； breast angiosarcoma ； magnetic resonance imaging ； diagnosis