Parameters on Renal Shear Wave Elastography Rather Than B-Mode Sonography Are Associated With Chronic Kidney Disease Stages and the Disease Progression

Hung-Hsien Liu ； Chun-Bi Chang ； Kun-Hua Tu ； Ting-Wen Sheng ； Chen-Chih Huang ； Yon-Cheong Wong ； Li-Jen Wang

《Journal of Radiological Science》 46卷 (2021/03) Pp. 207-214

https://doi.org/10.6698/JRS.202103_46.0037

摘要

PURPOSE. This retrospective study investigates the associations between the imaging parameters of renal conventional B-mode ultrasound (US) and shear wave elastography (SWE) with chronic kidney disease (CKD) stages and their progression MATERIALS AND METHODS. From December 2015 to March 2017, 38 consecutive patients underwent renal conventional B-mode US and SWE in our department. Their demographics and CKD stages were recorded at the time of the renal SWE. We also followed up their CKD stages regularly for the progression of CKD stages. The CKD stages were recorded at progression. The association between the imaging parameters of the renal elastography and CKD stages, as well as the progression of CKD stages, were analyzed. RESULTS. Of the 38 enrolled patients, 8 patients were male, and 30 were female. The patients had a median age of 40.5 years. There were no significant differences in the kidney length, width, and parenchymal thickness between CKD stages 3b-5 and 1-3a. By contrast, there was a significant difference in the renal shear wave velocity (SWV) between initial CKD stages 3b-5 and 1-3a (1.82 vs. 2.57 m/s, p = 0.02). In total, 18 (47.4 %) of the 38 patients showed CKD stage progression during follow-up, and renal SWV ≥ 2.95 m/s was associated with CKD stage progression. CONCLUSION. A higher SWV measured by the renal SWE was associated with an earlier CKD stage, and patients with higher SWV measurements may be prone to CKD stage progression. Renal SWE may have the potential for evaluating CKD stages and monitoring their course.

關鍵字

kidney ； elastography ； shear wave elastography ； chronic kidney disease ； ultrasound ； progression