Reversible cerebral vasoconstriction syndrome (RCVS) represents a group of conditions that exhibit reversible multifocal narrowing of the cerebral arteries, with clinical manifestations typically including thunderclap headache. Here, we report the case of a 53-year-old woman presenting with severe headaches associated with defecation. One month after the onset of the headaches, computed tomography angiography revealed a typical radiological finding of RCVS with multifocal narrowing of cerebral arteries. Normalization of the affected arteries, demonstrated by follow-up computed tomography angiography, may also be employed as an additional diagnostic criterion for RCVS.