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Xanthogranulomatous Mastitis Mimicking as Breast Cancer on F-18 FDG PET/CT

正子造影下表現形似乳癌的黃色肉芽腫乳腺炎

摘要


An 83-year-old woman underwent F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography for non-invasive evaluation of pleural effusion and pericardial effusion. The scan incidentally revealed an FDG-avid lesion in the right breast with lymph nodes in the right internal mammary chain. Core needle biopsy on the same day showed foamy histiocytes infiltration mixed with foreign-body type giant cells, pigmentation, cholesterol clefts, and inflammatory cell infiltration, indicating xanthogranulomatous mastitis. Cytokeratins AE1/AE3 immunostain was negative, which indicated no evidence of malignancy. There is no definite evidence of tumor growth in the right breast during a 2-year follow-up.

並列摘要


一位83歲女士罹患肋膜積水及心包膜積水,為尋求非侵入性的診療而接受正子掃描。正子掃描發現右側乳房結節及同側內乳淋巴結病灶。同日,粗針切片顯示泡沫樣組織球(foamy histiocytes)浸潤混有異物巨細胞(foreign-body giant cells)、色素沉著(pigmentation)、膽固醇裂(cholesterol clefts)及發炎細胞浸潤(inflammatory cell infiltration),病理診斷為黃色肉芽腫乳腺炎。Cytokeratins AE1/AE3免疫染色為陰性,指出無惡性細胞。經兩年追蹤觀察,右側乳房沒有新發現惡性腫瘤的跡象。

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