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  • 學位論文

時域擬光譜法模擬分析虛擬雞角膜的透明性

PSTD Simulation Analysis of the Optical Transparency of a Virtual Chicken Cornea

指導教授 : 曾雪峰
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摘要


在這項研究中,通過時域擬光譜法(pseudospectral time-domain algorithm, PSTD algorithm)模擬技術對通過虛擬雞角膜組織傳播的光進行建模。 建立了由膠原纖維組成的基質層,我們模擬了光在其中傳播的情形。並分析各種結構因素以研究其對光學透明度的影響,包括膠原纖維的排列和大小。此外,我們利用徑向分布函數對照膠原纖維的分布,並使用透射率,空間相關性和雷達散射截面(radar cross-section, RCS)分析角膜的透明性。我們可以從該研究的模擬結果中獲取有助於了解雞角膜透明度的光學信息。

關鍵字

角膜 膠原纖維 時域擬光譜法 透明性

並列摘要


In this research, the light propagation through a virtual chicken cornea tissue is modeled by the pseudospectral time-domain(PSTD) simulation technique. The stromal layer which is composed of collagen fibrils is established and we simulate light propagating through it. Various geometrical factors are analyzed to investigate the effect on optical transparency, including the arrangement and size of the collagen fibrils. Furthermore, the transmittance, spatial correlation, and radar cross-section are used to analyze the characteristics of light. Simulation findings of this research may help us acquire fundamental information that influencing the transparency of the chicken cornea.

參考文獻


Meek, Keith M, and Carlo Knupp, "Corneal structure and transparency," Progress in retinal and eye research, vol. 49, pp.1-16, 2015.
Young L Kim, Joseph T Walsh Jr, Thomas K Goldstick and Matthew R Glucksberg, “Variation of corneal refractive index with hydration,” Physics in medicine and biology, vol. 49, pp. 859-868, 2004.
Komai, Yoshiko, and Tatsuo Ushiki, "The three-dimensional organization of collagen fibrils in the human cornea and sclera," Investigative ophthalmology visual science, vol. 32, pp. 2244-2258, 1991.
Meek K., "The Cornea and Sclera," Collagen: Structure and Mechanics, pp.359-396, 2008.
Ritchey, Eric R., et al., "The chicken cornea as a model of wound healing and neuronal re-innervation," Molecular vision, vol. 17, pp.2440-2454, 2011.

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