- 學位論文
產製人類肺表面張力蛋白質 B/C 基因轉殖小鼠之研究
Generation of Transgenic Mice Harboring Human Pulmonary Surfactant-related Protein B/C Genes
摘要
3 摘要 本研究主旨在探討小鼠原核胚經雙基因共同注射後，於體外培養至二細 胞時期再進行胚移置對產製攜帶雙基因轉殖小鼠效率之影響。轉殖基因之構築 係以乳腺專一表現之牛
並列摘要
74 英文摘要 Generation of Transgenic Mice Harboring Human Pulmonary Surfactant-related Protein B/C Genes Yun-Yi Ma Abstract The purpose of this study was to investigate the effect of advanced culture to two-cell stage prior to co-injected mouse eggs on pups born and transgene integration efficiency by pronuclear gene microinjection. Transgenes were constructed by using a mature surfactant protein B (mSP-B) and C (mSP-C) cDNA fragment equipped with bovine
參考文獻
藤儒錚，吳宗瑾，江伯倫，謝豐舟。1997。早產兒的營養法。當代醫學，24（7）：
Abrams, S. A. 2001. Chronic pulmonary insufficiency in children and its effect on
antipeptide antibodies. J. Bio. Chem. 269: 20318-20328.
T. M. Townes. 1989. Synthesis of functional human hemoglobin in transgenic
mice Science.vol.245: 971-973.
延伸閱讀
- 鄭鼎彥（2014）。TGF-β誘發小鼠肺部幹/前驅細胞之分化之研究〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2014.10337
- Tsao, P. N., Li, H., Wei, S. C., Ko, M. L., Chou, H. C., Hsieh, W. S., & Hsieh, F. J. (2004). 促進血管生成因子及其接受器在出生後小鼠發育中肺臟的表現. Journal of the Formosan Medical Association, 103(2), 137-143. https://doi.org/10.29828/JFMA.200402.0009
- Liu, Y. L. (2010). 小鼠肺部幹細胞與具有均一孔洞之明膠生物支架於肺部組織工程上之應用 [master's thesis, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2010.01674
- 李燕儒（2006）。利用牛α-乳白蛋白啟動子驅動人類B型與C型肺臟表面張力相關蛋白之轉殖基因小鼠產製〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2006.10197
- Chou, F. Y. (2004). A novel gene, BC1, contributes to oncogenic transformation in vitro and in vivo [master's thesis, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2004.01271