學習障礙兒童的長程聽覺誘發波變化

目的: 長程聽覺誘發波可以闡述個體對聲音刺激的反應及其認知活動. 本研究的目的在於探討學習障礙兒童的長程聽覺誘發電位變化. 方法: 本研究篩選學習障礙的學齡兒童(8-13歲)共65人,另取年齡相當的正常兒童63人為對照組; 兩組兒童均接受長程聽覺誘發電位檢查,分析N200和P300波的振幅及潛值變化. 學障組的受試者同時需接受包括魏氏兒童智力測驗的完整心理衡鑑施測. 結果: (1)學障組與正常對照組比較,在頂葉電極(Pz)紀錄點上,學障組的N200及P300有顯著的潛時延長; P300振幅降低,N200振幅則增加. (2)學齡兒童的N200及P300潛時值,不論是正常或學障組,均隨年齡增加而縮短;而和性別無關. (3)學障組的N200,P300波的振幅及潛值和兒童魏氏智力分測驗商數無明顯相關性. 結論: (1)N200和P300潛時延長表示學障兒童在處理外界訊息的認知歷程中,訊息的區辨與鑑別,評估及作出決定的能力有障礙; P300振幅變小及N200振幅增加則代表學障者對刺激型態的辨別及對刺激反應的注意力也出現問題. (2) N200,P300波的振幅及潛值兒童和魏氏智力分測驗商數無明顯相關性.

關鍵字

長程聽覺誘發波；學習障礙； P300 ； N200

並列摘要

Objectives: Long-latency auditory evoked potentials can assay the physiological response to external acoustic stimulus and cognitive behaviors. In this study, the electro- physiological change was demonstrated in children with learning disability (LD). Methods: 65 children with learning disability (LD) and 63 normal children ranging in age from 8 to 13 years were enrolled in the “auditory oddball” event-related potential paradigm. The amplitude and latency of N200 (N2) and P300 (P3) components were studied in both groups. The Wechsler Intelligence Scale for Children-Third Edition (WISC-III) was also investigated in LD group. Results: (1) Subjects with LD had prolonged N2 and P3 latencies at Pz electrodes; peak amplitudes were found to decrease in P3 and increase in N2 components. (2) Our result indicates that N2 and P3 latencies during childhood decreases with age in normal and LD groups; not associates with gender. (3) Correlations between N2-P3 components and neuropsychological measures did not exist. Conclusions: This study indicates that N2 and P3 latency is significantly prolonged in children with LD; it suggests the dysfunction in the cognitive process of categorization, discrimination, evaluation and decision to external stimulus. The changes in amplitude suggest abnormalities in motivation and attention. Based on our current data, ERP component does not associate with WISC-III subtest.

並列關鍵字

auditory event-related potentials ； learning disability ； P300 ； N200

參考文獻

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國際替代計量

學習障礙兒童的長程聽覺誘發波變化

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