以金/銀奈米長方體製作為非酶電化學葡萄糖感測器

Au@Ag Nanocuboids for Nonenzymatic Electrochemical Glucose Sensor

黃詠寧(Huang Yong-Ning)

指導教授 ： 陳家俊

國立臺灣師範大學/理學院/化學系/碩士(2020年)

https://doi.org/10.6345/NTNU202000676

摘要

隨著生活質量的改善，糖尿病的發病率也越來越普遍。葡萄糖的檢測對於糖尿病患者日常生活中的臨床管理至關重要。因此，高穩定性且反應快速的葡萄糖監測方法的開發一直是活躍的研究領域。近年來，研究人員一直致力於開發無酶電極材料，以替代市售的基於酶的電極。非酶葡萄糖感測器由於其諸如穩定性，簡單性，可再現性和低成本的優點而迅速發展。非酶電化學葡萄糖感測器不僅需要良好的電子轉移能力，而且還需要較大的有效面積來進行快速的氧化還原反應。在本篇論文中，我們測試了具有核-殼結構的Au@Ag奈米長方體及其他奈米材料對葡萄糖在pH 8.4時的電化學敏感性，並將其塗布於金電極上作為無酵素葡萄糖感測器。我們使用循環伏安法進行測試。在-0.2V–0.4V（vs Ag / AgCl）的掃描範圍內，可以獲得葡萄糖氧化的電流響應。葡萄糖的線性範圍是2 mM–9 mM。

關鍵字

金/銀奈米長方體 ； 三極式電化學 ； 非酶葡萄糖感測器

並列摘要

As the quality of life improves, the incidence of diabetes is also becoming common. The detection of glucose is crucial for clinical management of diabetic patients in daily life. Thus, the development of reliable and rapid glucose monitoring methods has been an active research area. In recent years, the researchers have been focused on the development of enzyme-free electrode materials as an alternative to commercially available enzyme-based electrodes. Non-enzyme glucose sensors are rapidly being developed because of their advantages, such as stability, simplicity, reproducibility, and low cost. The non-enzyme electrochemical glucose sensor not only requires good electron transfer ability but also a large effective area for the rapid redox reaction. Here, we tested the electrochemical sensitivity of Au@Ag nanocuboids and other nanomaterialsto glucose at pH 8.4, which have a core-shell structure and used them coating on the gold electrode as an enzyme-free glucose sensor. We used cyclic voltammetrys for testing. In the scan range of -0.2V–0.4V (vs Ag / AgCl), the current response of glucose oxidation can be obtained. The linear range of glucose is 2 mM–9 mM.

並列關鍵字

Au@Ag nanocuboids ； three-electrode electrochemical ； non-enzymatic glucose sensor

參考文獻

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