臺東縣土雞傳染性滑膜炎流行病學調查

Epidemiological Study on Infectious synovitis of Native Chickens in Taitung Country

邱任賦

指導教授 ： 廖明輝教授

國立屏東科技大學/農學院/熱帶農業暨國際合作系所/碩士(2010年)

https://doi.org/10.6346/NPUST.2010.00022

摘要

中文摘要

學號：N9622020 總頁數：86
論文名稱：臺東縣土雞傳染性滑膜炎流行病學調查
學校名稱：國立屏東科技大學
系(所)：熱帶農業暨國際合作研究系(所)碩士在職專班
畢業時間及摘要別：九十八年度第一學期碩士學位論文摘要
研究生：邱任賦 指導教授：廖明輝 教授
論文摘要內容：
雞隻傳染性滑膜炎(Infectious Synovitis)的主要病原Mycoplasma synoviae，在黴漿菌的分類上是屬於Type S。自93年起至97年統計本縣近五年來檢驗家禽病例共224件，家禽關節炎的病例數有72件，其中傳染性滑膜炎即佔關節炎病例約45%(32件)。死亡率雖不高(少於1%)，但其發生率極高，雞隻常因關節炎而導致運動障礙、消瘦及生長不良等症狀使淘汰率升高，造成有色肉雞經濟損失的重要原因之ㄧ，因而造成養禽戶損失嚴重。本次研究藉由血清學檢查Mycoplasma synoviae感染情形，93-97年陽性率22.7％～100％。96-97年進行雛雞採檢，於入場約50日齡時進行後續追蹤，成功分離出96C03.04.05.09及97C02.06.13.14共8株Mycoplasma synoviae，經基因序列與GeneBank中登錄為AE017245.1的Mycoplasma synoviae 53比對後相似度為96.2%～99.5%。選定10場在94-97年間感染Mycoplasma synoviae進行相關資料彙整，發現若降低平均飼養隻數則有助降低感染率。此外，統計94-97年間病例，亦可發現平均飼養隻數降低，病例數亦隨之降低，反之則病例數增加。93-97年送檢病例統計結果病例多集中在3-5月及9-11月間，好發於養禽場集中之地區，發病雞齡以1-2月齡偏多。

關鍵字：傳染性滑膜炎、關節炎、流行病學

關鍵字

傳染性滑膜炎 ； 關節炎 ； 流行病學

並列摘要

Abstract
Infectious synovitis (IS) is caused by Mycoplasma synoviae that belongs to type S group of Mycoplasma classification . In this study , 224 cases of avian diseases were recorded in 5 years (2004～2008) . Among them , 72 cases were avian arthritis , and 32 out of the 72 cases (45％) were caused by IS . Although the mortality rate of IS is low , the incidence remains very high . Clinical signs of the affected chickens include motion disabilities , weakness , and poor growth performance . This is one of the most important economical losses for poultry breeders . In this study , serological analysis was used to moniter the situation of infections induced by Mycoplasma synoviae , The ratios of positive from 2004 to 2008 varied from 22.7％ to 100％ . By tracing the day-old chicks for 50 days , 8 different groups of Mycoplasma synoviae were isolated successfully . Comparative analysis of the genomes from this study and 53 Mycoplasma synoviae genomes from the GeneBank (AE017245.1), indicated high similarity of 96.2%～99.5% . Data form 10 farms that were infected with Mycoplasma synoviae between 2005-2008 showed that decreasing the number of chickens can reduce the rate of infection greately . Statistical analysis of the cases form 2005-2008 , confirmed this finding . The incidence of this disease tends to increase from March to May and September to November . Those farms with a high density had higher disease outbreaks and more incidences in chicken between 1 to 2 months old .

Keywords: Infectious Synovitis, arthritis,Epidemiology

並列關鍵字

Infectious Synovitis ； arthritis ； Epidemiology

參考文獻

Avakian,A.P.,and S.H.Kleven(1990a)Evaluation of SDS-polyacrylamide gel electrophoresis purified proteins of Mycoplasma gallisepticum and Mycoplasma synoviae as antigens in a dot ELISA.Avian Dis 34: 575-584.

Avakian,A.P.,and S.H.Kleven(1990b)The humoral immune response of chickens to Mycoplasma gallisepticum and potential causes of false positive reactions in avian Mycoplasma serology.Zentralbl Bakteriol Mikrobiol Hygsuppl 20:500-512.

Avakian,A.P., D.H. Ley, and S.H.Kleven(1992) Comparison of Mycoplasma synoviae isolates by immunoblotting.Avian Pathol 21:633-642.

Avakian,A.P.,and D.H.Ley (1993b)Protective immune response to Mycoplasma gallisepticum demonstrated in respiratory-tract washings from M.gallisepticum- infected chickens.Avain Dis 37:697-705.

Barbour,E.K.,J.A.Newman,J.Sasipreeyajan,C.A.Caputa, and A.M. Muneer. (1989)Identification Of the antigenic components of the virulent Mycoplasma gallisepticum(R) in chickens:their role in differentiation