Dong Van Karst Plateau is a plateau that spreads out along four counties of Ha Giang Province which includes Quan Ba, Yen Minh, Dong Van, Meo Vac. The plateau government has now placing more and more dominant concerns to find solutions for eradicating hunger and alleviating poverty for people of Dong Van. Additionally, with the unstable growth of economy, Dong Van Karst Plateau is facing many opportunities and difficulties for expanding plan to reach to the top economy of Ha Giang Province. In this context, the study is written with focus on key factors that impact directly to the hunger eradication and poverty alleviation in Dong Van Karst Plateau. Quantitative research is applied and achieved results showed that 4 factors (capital for production, capital for cultivable land, capital for family member, education of households) can explain for 64% of changes in income of poor people in Dong Van Plateau area. Furthermore, beta value of these factors is 0.362, 0.402, 0.391, and 0.459 and it was indicated that education of household had highest impact to income of poor people. Additionally, all these items were statistical significant.