Vietnam exhibits the second fastest growing and largest oil-exporting economy in Asian region for recent decade. The growth of the Vietnam gross domestic product was accompanied by falling oil exports. At the same time, the fast growing Vietnam stock market was also gone along with this trend. The connection between international oil price and Vietnam stock market index has become an obviously hot issue. This paper investigates the relationships between international oil price return and Vietnam stock index return. We use a simple regression model of daily data for the period 2007–2013 and include the foreign exchange rate (US/VND) to control the effect of US as the largest exporting country for Vietnam. The empirical result shows that international oil price return is positively and statistically significant correlated with Vietnam stock index return. The finding also indicates a very strong negative relationship between international oil price return and the foreign exchange rate return. This is a finding provide a new insight into the relationship between international oil price return and Vietnam stock market index return. It also leads to a meaningful implication for policymakers, investors, and risk managers participating Vietnam stock markets.