Since late 2019, Severe Acute Respiratory Syndrome coronavirus type 2, the newly discovered coronavirus, results in an ongoing and severe pandemic of Coronavirus disease-2019 (COVID-19). It leads to global health, political, and economic crises. In view of its communicability, risk of reinfection, and asymptomatic infection, vaccination becomes the most potential way of curbing the global spread of COVID-19 and controlling the pandemic. Until October 15, 2020, there were 42 candidate vaccines in clinical trials. Herein, we introduce the current status and prospects of COVID-19 vaccine development and associated issues.
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