The present study aims to investigate the accuracy of camera-based color measurement under periodical vibrating printing conditions. A high speed motor with crooked color disks were used to simulate the periodical printing vibration. The amplitude was between 1 to 4 mm to simulate a high speed web printing at 18,000 revolutions per hour. The results show that the mean color differences measured by the camera was as high as 4.2 E compared with static state. The differences are big enough to cause worng quality control. The results suggest a more sophisticated camera-based system is needed to achevie accuracy color measurement in the vibrating conditions.