The article is to describe the history and the definition of Pivotal Response Treatment (PRT). The PRT intervention includes three major goals, and four critical components, including the intervention settings, the amount of intervention, the intervention agents, and the target behaviors, The PRT intervention targets on the four pivotal areas of children's development, such as motivation, responsivity to multiple cues, social initiations, and self-management. The teaching approach and process on the four areas are provided. At last, eight teaching strategies on PRT are summarized for educators. The effectiveness of PRT intervention also addressed.