中華民國眼科醫學會雜誌
- OpenAccess
中華民國眼科醫學會,停刊
選擇卷期
- 期刊
- OpenAccess
為了研究冷凍療法及電氣燒灼術對眼球生長之影響。我們研究24隻紐西蘭白兔，12隻施行冷凍療法，12隻施行電氣燒灼術。手術施行於三至四週大白兔之右眼，左眼當做對照組。手術均施行於赤道部前面360°，避開長睫動脈及神經。眼球各徑長（包括前房深度、水晶體厚度、眼軸長度）及眼壓在手術前及術後每個月追踪檢查，直至三個月大為止。結果發現電氣燒灼術之眼球明顯地比對照眼為小。而冷凍療法也比正常對照眼為小，但只有在第二個月是有意義之差別。前房深度、水晶體厚度、眼壓在手術眼及對照眼並無有意義之差別。由病理組織切片，我們發現電氣燒灼術後之鞏膜很明顯地比臨近的正常鞏膜為薄，而冷凍療法則並無差異。所以，週邊網膜破壞術（冷凍療法及電氣燒灼術）能控制眼球之生長主要可能經由網膜和鞏膜的作用。
- 期刊
- OpenAccess
Scleral buckling surgery frequently induces geometrical change of eyeball contour, so the axial length and refraction may also be changed. We prospectively collected 33 cases of rhegmatogenous retinal detachment with fovea attached to evaluate the change of axial length and refraction after scleral buckling. The follow up peroid was at least 6 months. For all cases after scleral buckles, it caused an average increase of axial length as 0.41 mm (p＜0.01) and refractive change of -0.32D (p＜0.01). For encircling buckles subgroup, it caused an average increase of axial length as 0.74 mm (p＜0.01) and refractive change of -2.79D (p＜0.01). For non-encircling buckles subgroup, it caused an average increase of axial length as 0.14 mm (p=0.01) and refractive change of -0.09D (p=0.39). Eyes with encircling buckles have significant more change in axial length (p＜0.01) and myopia shifting (p＜0.01) than eyes without encircling buckles.
- 期刊
- OpenAccess
視網膜靜脈阻塞是網膜血管疾病第二常見的疾病。我們觀察分析馬偕醫院近十年至少追蹤三個月以上的七十三位病患，以螢光眼底血管攝影結果區分為缺血型(53.4%)、非缺血型(19.2%)、不確定型(23.3%)、及轉變型(4.1%)。非缺血型視力預後多不錯，黃斑部囊狀水腫是影響視力主因；缺血型則視力預後不佳，有四例導致絕對性青光眼，三例視力僅餘光感。合併症產生於靜脈阻塞後半年是危險期，虹膜及網膜新生血管各約佔1/3，1/6發生新生血管性青光眼。轉變型則均在一年內性生轉變，最終視力小於0.1，而有一人產生合併症。
- 期刊
- OpenAccess
Fifty-nine eyes of fifty-one patients scheduled for extracapsular cataract extraction and posterior chamber intraocular lens implantation were randomly, double-blindly assigned to received either (1) pretreatment with one drop of diclofenac sodium 0.1 % four times per day for the day before surgery plus one drop of diclofenac sodium 0.1% every 30 minutes for four doses, beginning 2 hours before surgery along with the dilating drops; (2) pretreatment with one drop of indomethacin 0.1% with the same protocol as the previous prescribed; (3) pretreatment with one drop of normal saline as a placebo with the same protocol. The pupil size was measured before surgery and before IOL implantation. Aqueous cells and flare were assessed and intraocular pressure was measured on the first postoperative day. All surgeries were performed by the same surgeon. On the first postoperative day, anterior chamber inflammation was more severe in control group than experimental groups. The difference between groups 1 and control group was statistically significant (p＜0.05). But the difference between experimental groups was not statistically significant (p＞0.05). There was no statistically significant difference in the amount of surgical-induced miosis and in the members of eyes with raised post-operative intraocular pressure among these three groups. We concluded that the pretreatment with an NSAID, either diclofenac sodium 0.1% or indomethacin 0.1%, before extracapsular cataract extraction with intraocular lens implantation can reduce the early postoperative anterior-chamber inflammation.
- 期刊
- OpenAccess
即使已有相當多藥物或手術的治療方式被發表過，復發仍是翼狀贅片治療上最大的隱憂。所以在使鞏膜裸露的簡單切除之外，不斷地有許多更有效的附加治療方式被發表過，Mitomycin C即是其中一種；本報告的目的即在比較Mitomycin C與其他附加治療的效果。對於初次復發的翼狀贅片，我們比較了Mitomycin C與結膜瓣移植的效果，結果顯示術中單次使用Mitomycin C與結膜瓣移植的術後復發率並不具統計上有意義的差異(P=0.09)；而對於原發性翼狀贅片，我們則比較了Mitomycin C與Thio-tepa的效果，結果顯示術中單次使用Mitomycin C與Thio-tepa術後點眼的復發率具有統計上有意義的差異(P=0.02)。另一方面，在本報告中所有使用Mitomycin C的病例皆未見嚴重的併發症。藉向這個研究結果，我們認為對於復發性的翼狀贅片術中單次使用Mitomycin C與結膜瓣移植的效果並無差異；而對於原發性翼狀贅片術中單次使用Mitomycin C 則較Thio-tepa術後點眼有效。
- 期刊
- OpenAccess
雷斯－巴克(Reis-Bücklers')角膜失養症是一種影響到角膜表皮的基質細胞，Bowman氏層，基質前層的一種角膜失養症。而其變異型Thiel-Behnke's失養症與其有共同的一些特色：反覆性的表皮破損及晚期時視力的喪失。本研究側重於一有家族病史的四十六歲男子經診斷為Thiel-Behnke's失養症的角膜前部顯微結構。構造中發現多處表皮基膜的缺乏、Bowman氏層的破壞、及位於表皮基膜與Bowman氏層間典型的”peculiar-curly”纖維的沉積。
- 期刊
- OpenAccess
使用Mitomycin-C術後點眼，目前已廣泛應用於降低翳狀贅片術後之復發率，但仍偶有嚴重併發症的發生。我們報告壹例翳狀贅片術後，僅點用少量Mitomycin-C後，在短時間內角膜融化變薄之病例。壹63歲男性接受裸露鞏膜手後，經Mitomycin-C (0.5mg/mL)點眼五次後，角膜發生融化變薄，二個月後發展成角膜穿孔，經實行嵌片式移植(patch graft)手術，眼球得以保持。向本例顯示即使少量Mitomycin-C之使用，仍可能造成嚴重之併發症。