Low Frequency of Target Organ Damage in Taiwanese with White Coat Hypertension

有白袍高血壓之臺灣人的低頻度目標臟器損傷

曾淵如(Yung-Zu Tseng) ； 江福田(Fu-Tien Chiang) ； 許寬立(Kwan-Lih Hsu) ； 駱惠銘(Huey-Ming Lo) ； 曾春典(Chuen-Den Tseng) ； 林俊立(Jiunn-Lee Lin) ； 黃瑞仁(Juey-Jen Hwang) ； 賴淩平(Ling-Ping Lai)

《Journal of the Formosan Medical Association》 104卷5期 (2005/05) Pp. 327-332

https://doi.org/10.29828/JFMA.200505.0004

並列摘要

Background and Purpose: The clinical importance of white coat hypertension (WCH) remains to be clarified. This study investigated the target organ damage in Taiwanese with WCH.
Methods: A total of 188 consecutive Taiwanese (88 men and 100 women), aged 26 to 15 years who had an abnormal office casual blood pressure (systolic blood pressure ≥140mm Hg or diastolic blood pressure ≥90mm Hg or both) and a normal ambulatory blood pressure (ABP) average (systolic ABP average ＜140mm Hg and diastolic ABP average ＜90mm Hg) at the outpatient clinic or from a mass survey were enrolled. Office casual blood pressure measurements were obtained by standard sphygmomanometric methods. Twenty-four-hour blood pressures were recorded by a commercial ambulatory pressure recorder (Del Mar Avionics, Model 1990 Pressurometer Ⅳ System). Hypertension-related target organ complications were assessed by electrocardiogram, chest X-ray, urinalysis and eye fundus examinations.
Results: Target organ damage was found in 6.4% of subjects with WCH. Roentgenographic left ventricular hypertrophy (LVH) was found in 1.1% of subjects and electrocardiographic LVH in 2.1%. Proteinuria was found in 1.6% of subjects and retinopathy in 1.1%. The frequencies of various target organ damage were not significantly associated with age, gender and the definition of normal ABP average as 135/85 mmHg or 140/90 mm Hg.
Conclusions: WCH represents a low-risk stratum for target organ damage in Taiwanese. These subjects should be identified and followed up regularly. The factors responsible for the low frequency of target organ damage in Taiwanese with WCH need further study.

並列關鍵字

Ambulatory blood pressure monitoring ； Blood pressure determination ； Left ventricular hypertrophy ； Proteinuria ； Retinal diseases