Title

Blood-Aqueous Barrier Function in a Patient with Combined Hamartomas of the Retina and Retinal Pigment Epithelium

Translated Titles

視網膜和視網膜色素上皮合併缺陷瘤之血液前房水柵功能

DOI

10.29828/JFMA.200507.0010

Authors

陳慕師(Muh-Shy Chen);張慶忠(Ching-Chung Chang);鄭碩方(Shuo-Fang Cheng);方怡謨(I-More Fan);侯平康(Ping-Kang Hou)

Key Words

Blood-aqueous barrier ; Hamartoma ; Photometry ; Pigment epithelium of the eye ; Retinal diseases

PublicationName

Journal of the Formosan Medical Association

Volume or Term/Year and Month of Publication

104卷7期(2005 / 07 / 01)

Page #

511 - 513

Content Language

英文

English Abstract

Clinical data showing breakdown in the blood-aqueous barrier in patients with combined hamartomas of the retina and retinal pigment epithelium are very limited. We used a laser flare-cell meter to examine blood-aqueous barrier function in a 35-year-old male patient who had typical combined hamartomas of the retina and retinal pigment epithelium characterized by an ill-defined, slightly elevated, grey-white epipapillary lesion with overlying glial proliferation and surrounding vascular tort1osity. Fluorescein angiography showed early hypofluorescence corresponding to the pigmented area with speckled hyperfluorescence in the lesion. Prominent retinal vascular tortuosity and late the leakage were noted in the late phase. Visual evoked potential demonstrated poor waveform. Laser photometry showed an increase in the aqueous flare intensity in the affected eye, as compared to the results in the unaffected eye and to data form normal subjects. The increase in the aqueous flare intensity in this patient suggests that the function of the blood-aqueous barrier may be affected in combined hamartomas of the retina and retinal pigment epithelium.

Topic Category 醫藥衛生 > 醫藥衛生綜合