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Assessing Current Nutritional Status of Patients with HCV-Related Liver Cirrhosis in the Compensated Stage

評估C型肝炎導致肝硬化且處於代償期的患者之營養現況

摘要


背景與研究目的:最近研究顯示有肝硬化的日本病人其營養狀態有很大歧異性,有些人是蛋白質熱量營養不良,但有些則是營養過剩及肥胖。為了建立恰當的膳食療養指引,瞭解病人目前的營養狀況是很重要的。方法:評估日本肝硬化病人營養攝取情形以及確認他們的營養問題。受試者皆非住院病人,有C型肝炎相關的肝硬化且處於代償期的患者47人、慢性C型肝炎46人、健康自願者32人。由註冊營養師協助受試者自行填寫一份簡短的飲食史問卷。結果:肝硬化病人根據其每天攝取的熱量及蛋白質分組,熱量及蛋白質攝取量在正常範圍內者占10.6%,攝取過多者占72.4%,不足者占17%。併發有糖尿病的肝硬化病人,其熱量、蛋白質、脂肪、醣類的攝取量顯著高於沒有糖尿病的病人。另外,肝硬化病人的熱量、蛋白質及脂肪的攝取量顯著高於慢性C型肝炎患者及健康受試者。在C型肝炎相關的肝硬化病人中,雖然有些人的熱量和蛋白質攝取有不足的情形,但大部分,尤其是同時患有糖尿病者,其攝取量是過多的。結論:對於肝硬化病人的營養管理,需適切地評估其各種營養素攝取情形及建立有效的營養教育系統。

並列摘要


Background/Aim: Nutritional states of Japanese patients with liver cirrhosis have recently shown great diversity, some show protein energy malnutrition and others excessive nutrition and obesity. For there to be adequate guidance regarding dietary treatment, it is important that a patient's current nutritional state be clarified. Methods: We assessed nutritive intake in Japanese cirrhotic patients and determined their nutritional problems. Subjects were non-hospitalized patients with hepatitis C virus (HCV)-related cirrhosis in the compensated stage (n=47), chronic hepatitis C (n=46) or healthy volunteers (n=32). A brief self-administered diet history questionnaire was conducted with assistance from a registered dietitian. Results: We categorized patients with cirrhosis according to daily intake of energy and protein; 10.6% had an energy and protein intake within a normal range, 72.4% showed excessive intake, and 17.0% showed insufficient intake of energy or protein. In cirrhotic patients with diabetic complications, the intake levels of energy, proteins, fat and carbohydrates were significantly higher than in patients without diabetes. Moreover, cirrhotic patients had significantly higher intake levels of energy, protein and fat than did chronic hepatitis C patients and healthy individuals. In patients with HCV-related liver cirrhosis, insufficient intake of energy and protein was shown in some, while many, especially those with diabetes, showed excessive intake. Conclusion: For nutritive management of cirrhotic patients, the intake of various nutrients should be appropriately assessed and effective nutritional education systems established.

並列關鍵字

liver cirrhosis HCV nutrition obesity chronic hepatitis C

被引用紀錄


洪憶雯(2016)。肝病防治方法之關鍵因素〔碩士論文,國立虎尾科技大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0028-1806201612571000

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