Title

抗精神类药物在化疗致呕吐不良反应的临床处理方法

Translated Titles

Clinical treatment for antidepressant drug adverse reaction caused by vomiting during chemotherapy

Authors

曾娟紫;广东省梅州市梅江区黄搪路梅州市人民医院化疗2科;曾娟紫;吴国武;广东省梅州市梅江区黄搪路梅州市人民医院化疗2科,广东 梅州,514031

Key Words

抗精神类药物 ; 化疗 ; 呕吐 ; 处理 ; 药物与临床 ; Antidepressant drugs ; Chemotherapy ; Vomiting ; Treatment

PublicationName

吉林醫學

Volume or Term/Year and Month of Publication

35卷12期(2014 / 05 / 08)

Page #

2534 - 2535

Content Language

簡體中文

Chinese Abstract

目的:探讨抗精神类药物用于化疗致呕吐不良反应中的应用方法及效果。方法:选择化疗致呕吐患者60例,依照床位单双号随机、平均分为研究组与对照组,对照组予以常规止吐处理,研究组在常规止吐基础上联合抗精神类药物奥氮平止吐,对比两组患者止吐效果和生活质量。结果:研究组患者治疗有效率为36.7%、无效率为63.3%,有效率明显高于对照组(P=0.013);研究组患者食欲、睡眠、生活、精神状态、沟通交往、生活乐趣改善率分别为56.7%、36.7%、43.3%、43.3%、26.7%、26.7%,改善率均高于对照组(P<0.05)。结论:抗精神类药物用于化疗致呕吐不良反应治疗中有确切的止吐效果,且能对患者食欲、睡眠、精神状态等起到调节作用,在止吐的同时改善生活质量。

English Abstract

Objective To investigate the use of antidepressant drugs inchemotherapy induced adverse reaction of vomiting in.Methods 60 cases ofvomiting caused by chemotherapy in patients,randomly,divided into the studygroup and the control group,the control group was given routine antiemetictreatment,research combined antidepressant Deanxit group routine antiemeticdrugs.Results The effective rate of patients in study group was 36.7%,no efficiency is 63.3%,the efficiency was higher than that of control group(P=0.013);the study group patients appetite,sleep,life,mental state,communication,the joy of the game of living improvement rate were 56.7%,36.7%,43.3%,43.3%,26.7%,26.7%,im provement rate was higher than that of control group(P<0.05).Conclusion Theanti depression drugs used for chemotherapy induced exactly the antiemetic effect of adverse reaction in the treatment of vomiting,and can improve the quality of life.

Topic Category 醫藥衛生 > 醫藥衛生綜合