Title

白细胞介素18与心绞痛患者左室射血分数的相关性研究

Translated Titles

The Research of Correlation of Interleukin-18 with Angina Pectoris Patients' Left Ventricular Ejection Fraction

Authors

张燕(Yan Zhang);黎莉(Li Li);张运(Yun Zhang);朱圆圆(Yuan-Yuan Zhu);王颖(Ying Wang);谭红伟(Hong-Wei Tan)

Key Words

内科学 ; 白细胞介素18 ; 心绞痛 ; 动脉粥样硬化 ; 左室射血分数 ; Angina pectoris ; Interleukin-18 ; Arteriosclerosis ; Left ventricular ejection fraction LVEF

PublicationName

泰山醫學院學報

Volume or Term/Year and Month of Publication

25卷5期(2004 / 10 / 25)

Page #

436 - 438

Content Language

簡體中文

Chinese Abstract

Aim To detect the peripheral venous blood' concentration of IL-18 in patients with UA and SA and evaluate it's correlation with angina pectoris patients' left ventricular ejection fraction. Methods Eighty hosipitalized patients were enrolled in this research since 2002.12 to 2004.01. Forty cases were UA, twenty cases were SA, twenty cases were normal controls. All patients were performed coronary artery angiography and Doppler echocardiography. IL-18 was measured with ELISA methods. Results The concentrations of IL-18 in UA and SA were much higher than controls', but there were no difference between these two. Patients with LVEF<50% had higher IL-18 concentrations than those with LVEF>50%. Conclusion IL-18 was positive correlated to coronary artery diseases, but no prediction to the stability of AS plaques. And it was nagtive correlated to Left ventricular ejection fraction (LVEF). So IL-18 had important values in prodiction of angina pectoris.

English Abstract

Aim To detect the peripheral venous blood' concentration of IL-18 in patients with UA and SA and evaluate it's correlation with angina pectoris patients' left ventricular ejection fraction. Methods Eighty hosipitalized patients were enrolled in this research since 2002.12 to 2004.01. Forty cases were UA, twenty cases were SA, twenty cases were normal controls. All patients were performed coronary artery angiography and Doppler echocardiography. IL-18 was measured with ELISA methods. Results The concentrations of IL-18 in UA and SA were much higher than controls', but there were no difference between these two. Patients with LVEF<50% had higher IL-18 concentrations than those with LVEF>50%. Conclusion IL-18 was positive correlated to coronary artery diseases, but no prediction to the stability of AS plaques. And it was nagtive correlated to Left ventricular ejection fraction (LVEF). So IL-18 had important values in prodiction of angina pectoris.

Topic Category 醫藥衛生 > 醫藥衛生綜合
醫藥衛生 > 預防保健與衛生學
醫藥衛生 > 藥理醫學
醫藥衛生 > 社會醫學