Title

糖尿病與冠脈支架再狹窄的關係分析

Translated Titles

Analysis the Relationship between Diabetes Mellitus and Coronary Stenting Restenosis

Authors

蘇林(Lin Su);劉學波(Xue-Bo Liu);葛均波(Jun-Bo Ge)

Key Words

糖尿病 ; 冠脈支架 ; 再狹窄 ; Diabetes mellitus ; Coronary stent ; Restenosis

PublicationName

中國臨床醫學

Volume or Term/Year and Month of Publication

12卷4期(2005 / 08 / 25)

Page #

578 - 580

Content Language

簡體中文

Chinese Abstract

目的:探討糖尿病與冠脈支架術後再狹窄的關係。方法:回顧性分析2000年6月~2002年3月成功進行PCI+Stenting治療並復查冠脈造影者134例冠心病臨床資料。根據直徑狹窄是否≥50%,將其分為再狹窄組和未再狹窄組,並分析冠心病相關危險因素與支架內再狹窄的關係,探討糖尿病是否為支架內再狹窄的獨立危險因素。結果:134例共置入181只支架,其中61例(75只)發生支架內再狹窄,6個月再狹窄率為41.2%。在無再狹窄組和再狹窄組男性分別占78.9%和89.8%(P=0.147)。兩組平均年齡(62.7±10.4歲)。高血壓患病率(58.9%vs65.6%),高血壓分級,高血壓年限,吸煙,入院TC,LDL,在統計學上無顯著差異。在冠心病的危險因素中,糖尿病病人在再狹窄組有12例占19.7%,無再狹窄組只有3例占4.2%(P=0.004);再狹窄組的入院血糖水平為5.70±1.56mmol/L,明顯高於無再狹窄組5.14±0.82mmol/L(P=0.01)。結論:糖尿病是支架內再狹窄最有力的預測因子,而入院時血糖水平可能是支架內再狹窄發生的獨立危險因子。

English Abstract

Objective: To study the relationship between diabetes mellitus and coronary instent restenosis (ISR). Methods: Restrospective analysed 134 patients with coronary heart disease who had under gone percutaneous coronary intervention (PCI+stenting) at the period from Jun 2000 to Mar 2002. After 6 months of implantation angioplasty was done in all patients. The patients whose coronary diameter 50% were divided into 2 groups: ISR group and non ISR group. This paper analysed the relation between risk factors of coronary heart disease and coronary in-stent restenosis. Among these risk factors to find out whether the diabetes mellitus was the independent risk factor for restenosis. Results: In 134 patients, 181 stents were implanted and 75 stents were restenosed (61 patients). The 6 month restenosis rate was 41.2%. Among 61 patients, 12 with diabetes mellitus (19.7%), while 73 non ISR group only 3 were diabetes mellitus (4.2%, P=0.004). Diabetes mellitus in ISR group was markedly increased. Moreover blood glucose in admission ISR group was 5.70±1.56mmol/L, non ISR group was 5.14±0.28mrnol/L (P=0.01). Blood glucose in ISR group was much higher than that of non ISR group. Conclusion: Blood glucose level could be an independent risk factor for the occurrence of in-stent restenosis, and increased the incidence of restenosis.

Topic Category 醫藥衛生 > 醫藥衛生綜合