Title

胰腺囊實性腫瘤4例報告及文獻復習

Translated Titles

Cystic and Soild Tumors of the Pancreas: Report of 4 Cases and Review of Literature

Authors

孫希印(Xi-Yin Sun);高虹(Hong Gao);呂德勇(De-Yong Lu)

Key Words

胰腺腫瘤 ; 免疫組織化學 ; 預後 ; Pancreatic neoplasms ; Immunohistochemisty ; Prognosis

PublicationName

中國臨床醫學

Volume or Term/Year and Month of Publication

12卷4期(2005 / 08 / 25)

Page #

717 - 718

Content Language

簡體中文

Chinese Abstract

目的:探討胰腺囊實性腫瘤(CSTP)的臨床病理及免疫組化特點。方法:4例CSTP常規作HE染色免疫組織化學(S-P法)染色觀察。結果:4例患者手術後均無復發。腫瘤較大,平均直徑6.25cm,有包膜,由囊性與實性區混合組成。鏡檢:腫瘤細胞圍繞纖維血管軸心排列成假乳頭突起為其特徵,細胞形態較一致,核圓形或卵圓形,異型性不明顯,核分裂相罕見。免疫組化:4例AACT(+),3例AAT(+),3例NSE(+),,2例Vimentin(+),2例PR(+),1例Keratin局灶(+),Des、ER、S-100蛋白、Syn均(-)。結論:胰腺囊實性腫瘤多發生於年輕女性,具有獨特的臨床病理特點和較高的手術治癒率,應視為交界性腫瘤。

English Abstract

Objective: To study the clinicopathologic and immunohistochemical characteristics of cystic and solid tumors of the pancreas (CSTP). Methods; 4 cases of CSTP were studied by histologic HE and immunohistochemistry (S-P method). Results: There were 3 female and 1 male patients aged from 25 to 56 (mean age 38) without recurrence after tumor resection. The tumors were larger in size (mean diameter 6.25cm). All encapsulated, and solid alternately with cystic. Histologically, Psudopapillary structure with a fibrovascular core was remarkable. They were uniformed population of cells, the nuclear was oval, round without atypia, and rate mitotic figures. Immunohistochemically, the tumors were positive for AACT (4 cases), AAT (3 cases), NSE (3 cases), Vimentin (2 cases), PR (2 cases), Keratin (1 case), but negative for Des, ER, S-100 and synaptophysin in all the cases. Conclusion: CSTP is a clinicopathologic entity in young female patients with a benign clinical course. It is a tumor of uncertain malignant potential (borderline).

Topic Category 醫藥衛生 > 醫藥衛生綜合