Background: Results of peritoneal function of peritoneal dialysis (PD) in cirrhotic patients is still open to debate. The aim of this study was to evaluate the peritoneal function of PD in cirrhotic patients. Methods: Between January 1998 and December 2002, 10 patients with both liver cirrhosis and uremia who were undergoing CAPD therapy at our PD center were enrolled in this retrospective study. The diagnosis of liver cirrhosis was based on clinical, biochemical and ultrasound studies without there being any histological evidence. 37 patients without cirrhosis (mean age 52.16±1.96 year-old) who started PD therapy in the same period were enrolled in this study as the control group. Results: The 4 hour creatinine D/P of cirrhotic patients were 0.83±0.19 and 0.62±0.09 for the control group (p<0.001). The Glucose D/D0 of cirrhotic patients were 0.31±0.12 and 0.41±0.08 for the control patients (p<0.005). Based on above results, the peritoneal equilibrium tests of liver cirrhosis patients tended to belong to a high transporter category. Conclusions: The peritoneal equilibrium test in cirrhotic patients with PD was found to distribute to a high transporter group in this study. The question of whether the tendency of the transporter category in cirrhotic patients is linked to the long-term survival rate of PD treatment requires further specific and controlled investigation.
Background: Results of peritoneal function of peritoneal dialysis (PD) in cirrhotic patients is still open to debate. The aim of this study was to evaluate the peritoneal function of PD in cirrhotic patients. Methods: Between January 1998 and December 2002, 10 patients with both liver cirrhosis and uremia who were undergoing CAPD therapy at our PD center were enrolled in this retrospective study. The diagnosis of liver cirrhosis was based on clinical, biochemical and ultrasound studies without there being any histological evidence. 37 patients without cirrhosis (mean age 52.16±1.96 year-old) who started PD therapy in the same period were enrolled in this study as the control group. Results: The 4 hour creatinine D/P of cirrhotic patients were 0.83±0.19 and 0.62±0.09 for the control group (p<0.001). The Glucose D/D0 of cirrhotic patients were 0.31±0.12 and 0.41±0.08 for the control patients (p<0.005). Based on above results, the peritoneal equilibrium tests of liver cirrhosis patients tended to belong to a high transporter category. Conclusions: The peritoneal equilibrium test in cirrhotic patients with PD was found to distribute to a high transporter group in this study. The question of whether the tendency of the transporter category in cirrhotic patients is linked to the long-term survival rate of PD treatment requires further specific and controlled investigation.
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