Title

Polycyclic Quinones and Hydroquinones, Antitumor Constituents from Taiwanese Marine Sponge Xestospongia Sp

DOI

10.7019/CPJ.200206.0207

Authors

沈雅敬(Ya-Ching Shen);羅光良(Kuang-Liang Lo);郭曜豪(Yao-Haur Kuo);Rupak Chakraborty

Key Words

Xestospongia ; Quinones ; Hydroquinones ; Cytotoxicity

PublicationName

The Chinese Pharmaceutical Journal

Volume or Term/Year and Month of Publication

54卷3期(2002 / 06 / 01)

Page #

207 - 213

Content Language

英文

English Abstract

Eight polycyclic quinines and hydroquinones were isolated from marine sponge Xestospongia spp. They are halenaquinone (1), halenaquinol (2), 14-methoxyxestoquinone (3), 15-methoxyxes-toquinone(4), xestoquinone (5), 15-chloro-14-hydroxyxestoquinone (6), adociaquinone A (7) and adociaquinone B (8). Biological screening revealed that compounds 7 and 8 possessed in vitro cytotoxicity against KB 16 and HEP-3B tumor cell lines.

Topic Category 醫藥衛生 > 藥理醫學