Title |
Polycyclic Quinones and Hydroquinones, Antitumor Constituents from Taiwanese Marine Sponge Xestospongia Sp |
DOI |
10.7019/CPJ.200206.0207 |
Authors |
沈雅敬(Ya-Ching Shen);羅光良(Kuang-Liang Lo);郭曜豪(Yao-Haur Kuo);Rupak Chakraborty |
Key Words |
Xestospongia ; Quinones ; Hydroquinones ; Cytotoxicity |
PublicationName |
The Chinese Pharmaceutical Journal |
Volume or Term/Year and Month of Publication |
54卷3期(2002 / 06 / 01) |
Page # |
207 - 213 |
Content Language |
英文 |
English Abstract |
Eight polycyclic quinines and hydroquinones were isolated from marine sponge Xestospongia spp. They are halenaquinone (1), halenaquinol (2), 14-methoxyxestoquinone (3), 15-methoxyxes-toquinone(4), xestoquinone (5), 15-chloro-14-hydroxyxestoquinone (6), adociaquinone A (7) and adociaquinone B (8). Biological screening revealed that compounds 7 and 8 possessed in vitro cytotoxicity against KB 16 and HEP-3B tumor cell lines. |
Topic Category |
醫藥衛生 >
藥理醫學 |