摘要
維生素D（vitamin D）是一群脂溶性的維生素，是維持人體正常生長及健康的重要營養素。人體可由攝取食物取得維生素D，也可由皮膚接受紫外線照射而自行合成維生素D。維生素D是具有多重生理作用的荷爾蒙，其傳統的功能為維持鈣磷的平衡及骨骼健康（skeletal health），除此之外，也有許多非骨骼健康（extra-skeletal health)方面的功能，包括腎臟保護的功能、心臟血管保護的功能、免疫調節的功能及預防癌症的功能等。維生素D缺乏（vitamin D deficiency）或不足（insufficiency）與許多疾病相關，也與死亡率較高相關。維生素D缺乏或不足並不少見，因此維生素D的的需求及補充也越來越被重視。本篇文章主要整理維生素D與人體健康的關係，包括骨骼健康及非骨骼健康，維生素D缺乏或不足對人體健康的影響與維生素D補充（vitamin D supplementation）可能的臨床效益。
並列摘要
Vitamin D is a group of fat-soluble secosteroids, and it is an important nutrient for human's normal growth and health. Humans obtain vitamin D from the intake of food containing it. Human body can also synthesize vitamin D in the skin by ultraviolet B radiation from sunlight. Vitamin D is a pleiotropic hormone, its classical function is to maintain calcium and phosphate homeostasis and skeletal health. Vitamin D also has many extra-skeletal functions, such as renoprotection, cardiovascular protection, immune modulation and cancer prevention. Vitamin D deficiency is associated with many acute and chronic illnesses and diseases and is also associated with high mortality. Vitamin D deficiency is not uncommon and vitamin D supplementation may have some benefits for human health. This article reviewed the relationship of vitamin D and human health, including skeletal and extra-skeletal health, vitamin D deficiency and its associated illnessess, vitamin D supplementation and its potential benefits.
被引用紀錄
延伸閱讀
- 李耀泰、陳福民、李逸剛、郭宗正（2016）。維生素D與癌症的檢視。婦癌醫學期刊，(44)，39-43。https://www.airitilibrary.com/Article/Detail?DocID=P20150521002-201610-201611140012-201611140012-39-43
- 王馨慧（2011）。維生素D與自體免疫疾病的關係。臺灣兒童過敏氣喘免疫及風濕病醫學會學會通訊，12(2)，11-12。https://doi.org/10.7025/CFSPIHHHHTH.201107.0011
- 楊榮森（2009）。維生素D妙用無窮。健康世界，(288)，6-6。https://doi.org/10.6454/HW.200912.0006
- 鄭憶文（2017）。成人維生素D營養狀況及其相關影響因素〔碩士論文，中山醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0003-2908201700105800
- Xie, Z. J., Santora, A. C., Shapses, S. A., & Wang, X. B. (2014). Vitamin D Binding Protein and Vitamin D Levels. International Journal of Endocrinology, 2014(), 349-350-139. https://doi.org/10.1155/2014/638263