Higher Hematogenous Metastatic Rate Associated with Thrombocytosis in Patients with Nasopharyngeal Carcinoma

血小板過高之鼻咽癌患者合併較高之血行轉移率

王博民(Po-Ming Wang) ； 黃淑珍(Shu-Chen Huang) ； 許博智(Poh-Chih Hsu) ； 丁禮莉(Lai-Lei Ting) ； 方麗麗(Lily Fong) ； 雷德(Louis Tak Lui)

《中華放射線醫學雜誌》 19卷3期 (1994/09) Pp. 229-234

摘要

One thousand one hundred and eighty-nine patients were treated in this hospital with radiation therapy for nasopharyngeal cancer from 1984 to 1989. Among them, 608 were eligible by retrospective analysis, according to their first visit platelet counts. Thrombocytosis or platelet counts＞400,000/ul was noticed at the initiation of radiotherapy in 37(6.1%)of the 608. They were been compared with those with normal platelet counts. The hematogenous metastatic rate for the 37 patients with thrombocytosis was 89.1%, whereas, for the 571 patients without thrombocytosis, it was 16.8% (P＜0.005). Thrombocytosis is a significant indicator of an increased hematogenous metastatic rate in patients with nasopharyngeal carcinoma.

關鍵字

血液，血小板 ； 鼻咽，腫瘤 ； 鼻咽，放射治療 ； 腫瘤，轉移

並列摘要

One thousand one hundred and eighty-nine patients were treated in this hospital with radiation therapy for nasopharyngeal cancer from 1984 to 1989. Among them, 608 were eligible by retrospective analysis, according to their first visit platelet counts. Thrombocytosis or platelet counts＞400,000/ul was noticed at the initiation of radiotherapy in 37(6.1%)of the 608. They were been compared with those with normal platelet counts. The hematogenous metastatic rate for the 37 patients with thrombocytosis was 89.1%, whereas, for the 571 patients without thrombocytosis, it was 16.8% (P＜0.005). Thrombocytosis is a significant indicator of an increased hematogenous metastatic rate in patients with nasopharyngeal carcinoma.

並列關鍵字

Blood, platelets ； nasopharynx, neoplasms ； nasopharynx, therapeutic radiology ； neoplasms, metastases