Title

跟骨定量超音波儀應用於健康篩檢之適當性評估

Translated Titles

Evaluation of the Application of Quantitative Ultrasound of the Calcaneus in Health Examination

Authors

羅煥鉅(Huan-Chu Lo);王梅芳(Mei-Fang Wang);黃立宗(Li-Chung Hwang);郭俞良(Yu-Liang Kuo)

Key Words

雙能X光骨密度儀 ; 骨質疏鬆 ; 定量超音波儀 ; 跟骨 ; Dual X-ray absorptiometry ; Osteoporosis ; Quantitative ultrasound ; Calcaneus

PublicationName

中華放射線醫學雜誌

Volume or Term/Year and Month of Publication

30卷4期(2005 / 08 / 01)

Page #

213 - 216

Content Language

繁體中文

Chinese Abstract

The aim of our study was to evaluate the difference and agreement between quantitative ultrasound (QUS) and dual X-ray absorptiometry (DXA) using statistical method, which is suitable for the health examination. Ninety-eight consecutive patients (female, 49±12 years old) of perimenopause were examined in this study. DXA of the lumbar spine was performed to acquire the BMD values and were expressed as T-score. At the same session, the calcaneus of the same patients was examined with QUS. Paired T-test and linear regression were performed to observe the relationship between QUS and DXA. The level of agreement was analyzed with weighted kappa (wk) statistics. The paired T-test for comparison of T-score of DXA and QUS showed t-value about 5.943 (P<0.001), which was statistical significance. Pearson's correlation coefficient for the comparison of QUS with DXA was R=0.714 (P<0.0001). Using single proportion test, the diagnostic percentage of osteoporosis was also significant difference (significant statistic) of between the DXA (11.2%) and QUS (20.4%) (Z=2.135, 0.028<P<0.03). By weighted kappa statistic of T-score, the diagnostic disagreement was found between QUS and DXA, the agreement was fair (kappa score =0.258, P<0.0001). QUS cannot replace DXA; it may be an alternative method for high-throughput screening tool for osteoporosis in health examination if it had been standardized as DXA. QUS is not recommended for diagnosis and monitoring of osteoporosis.

English Abstract

The aim of our study was to evaluate the difference and agreement between quantitative ultrasound (QUS) and dual X-ray absorptiometry (DXA) using statistical method, which is suitable for the health examination. Ninety-eight consecutive patients (female, 49±12 years old) of perimenopause were examined in this study. DXA of the lumbar spine was performed to acquire the BMD values and were expressed as T-score. At the same session, the calcaneus of the same patients was examined with QUS. Paired T-test and linear regression were performed to observe the relationship between QUS and DXA. The level of agreement was analyzed with weighted kappa (wk) statistics. The paired T-test for comparison of T-score of DXA and QUS showed t-value about 5.943 (P<0.001), which was statistical significance. Pearson's correlation coefficient for the comparison of QUS with DXA was R=0.714 (P<0.0001). Using single proportion test, the diagnostic percentage of osteoporosis was also significant difference (significant statistic) of between the DXA (11.2%) and QUS (20.4%) (Z=2.135, 0.028<P<0.03). By weighted kappa statistic of T-score, the diagnostic disagreement was found between QUS and DXA, the agreement was fair (kappa score =0.258, P<0.0001). QUS cannot replace DXA; it may be an alternative method for high-throughput screening tool for osteoporosis in health examination if it had been standardized as DXA. QUS is not recommended for diagnosis and monitoring of osteoporosis.

Topic Category 醫藥衛生 > 基礎醫學
Times Cited
  1. 吳惠瑩(2009)。中老年女性從事規律性運動社區舞蹈對下肢關節角度、膝關節肌力、骨質密度及平衡能力之影響。屏東科技大學休閒運動保健系所學位論文。2009。1-67。 
  2. 張淑芳(2007)。骨質疏鬆症智慧型健康風險評估於護理照護之實證研究。臺灣師範大學工業教育學系學位論文。2007。1-139。
  3. 賴瑞芬(2010)。應用類神經網路建構女性骨質密度預測模式。臺北醫學大學醫學資訊研究所學位論文。2010。1-52。