鼓室乳突腔之異位神經膠組織

Ectopic Neuroglial Tissue in the Tympanomastoid Cavity

劉俊欣(Chun-Hsin Liu) ； 林嘉德(Chia-Der Lin) ； 鄭元凱(Yuan-Kai Cheng) ； 陳志榮(Chi-Long Chen) ； 蔡銘修(Ming-Hsui Tsai)

《台灣耳鼻喉頭頸外科雜誌》 38卷3期 (2003/06) Pp. 130-134

https://doi.org/10.6286/2003.38.3.130

摘要

頭頸部異位神經膠組織通常表現於人體中線，如鼻腔或鼻咽部，而中耳之異位神經膠組織在臨床上則非常少見，過去文獻報告也不多。本報告為一名52歲女性，主訴多年左側耳漏並伴隨漸進性聽力障礙，經耳鏡檢查發現左耳膜後上象限有一凹陷袋；聽力檢查顯示左耳中度傳導性聽力障礙；電腦斷層掃描顯示左耳中耳及乳突腔充滿軟組織，同時並無明顯骨性之破壞。病人接受鼓室探查及乳突切開術，手術發現中耳及乳突腔充滿軟組織，軟組織並包圍聽小骨鏈，術中並無腦脊髓液漏，也無乳突蓋或聽小骨鏈缺失之發現。取下之中耳及乳突腔軟組織經病理學檢查，診斷為鼓室乳突腔之異位神經膠組織。因屬罕見，特提出報告。

關鍵字

異位神經膠組織 ； 鼓室乳突腔

並列摘要

Ectopic neuroglial tissues in the head and neck region often involve midline structures, including the nose and nasopharynx. Ectopic neuroglial tissue arising in the tympanomastoid cavity is rare, and we describe one such patient seen in July 2002. Her initial symptoms included a several year history of intermittent left otorrhea and progressive hearing impairment. On examination, a retracted pocket was found over the postero-superior quadrant of the left eardrum. An audiogram identified left-sided moderate conductive hearing loss. Computerized tomography identified a soft tissue mass infiltrating the left mastoid cavity and epitympaneum without bony destruction. An exploratory tympanotomy and mastoidectomy showed the soft tissue mass occupying the left mastoid cavity and surrounding the ossicular chain. Immunohistochemical staining for glial fibrillary acidic protein (GFAP) was positive. Histopathological examination identified ectopic neuroglial tissue. Ectopic neuroglial tissue is a rare cause of middle ear soft tissue masses that should be considered in the differential diagnosis of such lesions.

並列關鍵字

ectopic neuroglial tissue ； tympanomastoid cavity