Basaloid squamous cell carcinoma is a histologically distinct high grade, aggressive variant of squamous cell carcinoma. The head and neck region appears to be the most frequent area of occurrence of basaloid squamous cell carcinoma. However, it is found in other mucosal sites, such as the esophagus, lung, thymus, and anus. Basaloid squamous cell carcinoma is rarely found in nasal cavity and there are only 2 cases of basaloid squamous cell carcinoma of nasal septum reported by Wieneke et al. In October 2001, we experienced a 37-year-old man with basaloid squamous cell carcinoma on the right side of the nasal septum. His chief complaint was right nasal bleeding for more than one month. The patient underwent wide resection of the nasal septum by lateral rhinotomy procedure. No recurrence has been noted 16 months after surgery.