- 期刊
- OpenAccess
經濟評估在新生血管性老年性黃斑部病變新式治療之應用
Application of Economic Evaluations on Novel Interventions for Neovascular Age-Related Macular Degeneration
摘要
黃斑部病變(age-related macular degeneration, AMD)衍生出來的沉重疾病負擔，蘊涵著極大的公共衛生問題。過去幾年，新治療方法問世，老年性黃斑部病變的預後因而有重大突破。新生血管性老年性黃斑部病變病人接受抗血管內皮生長因子療法[anti vascular endothelial growth factor (anti-VEGF) therapy]後，視力及生活品質可能獲得改善。然而，種種新式治療策略卻帶來前所未有的醫療成本。本文藉回顧相關期刊論文，介紹如何運用經濟評估在新生血管性老年性黃斑部病變的新式治療，並討論經濟評估分析上的議題及限制。隨著「成本效用分析」(cost-utility analysis, CUA)在醫療照護科技評估上逐漸扮演重要角色，其分析結果所呈現的資料，可幫助決策者做資源分配。
關鍵字
無資料並列摘要
Economic evaluations of health care interventions have become more and more important because of limited resources, with ophthalmic health care being no exception. Owing to its heavy burden, age-related macular degeneration (AMD) poses enormous public health implications. In the past few years, the emergence of new treatment modalities has revolutionized the prognosis of neovascular AMD. Patients of neovascular AMD may experience improvement in vision and quality of life after anti-vascular endothelial growth factor (anti-VEGF) therapy. However, many of these novel treatment strategies bring unprecedented levels of costs. This article introduces the application of economic evaluations by reviewing studies on new treatments of neovascular AMD. The analytic issues and limitations of economic evaluations were discussed. As cost-utility analysis (CUA) gradually plays an important role in health care technology assessment, its result may provide decision-maker information to facilitate resource allocation.
延伸閱讀
- 陳瑩山（2007）。黃斑部病變 確認“脈絡膜新生血管”是治療關鍵。健康世界，(255)，53-59。https://www.airitilibrary.com/Article/Detail?DocID=16077059-200703-x-255-53-59-a
- 鄭成國（2020）。濕性年齡相關性黃斑部病變的治療策略探討：主動先發型（Proactive）或被動反應型（Reactive）。台北市醫師公會會刊，64(1)，23-29。https://www.airitilibrary.com/Article/Detail?DocID=P20110322001-202001-202001170005-202001170005-23-29
- Lo, Y. L., Cheng, C. K., Peng, C. H., Lee, T. S., Hu, C. C., Wu, T. E., Lin, H. C., Peng, P. H., Bai, C. H., & Lin, H. S. (2008). 眼內注射BEVACIZUMAB治療老年退化性黃斑部病變之療效－短期結果報告. 中華民國眼科醫學會雜誌, 47(1), 12-22. https://doi.org/10.30048/ACTASOS.200803.0003
- Stewart, M. W. (2013). Review of Aflibercept for the Treatment of Neovascular Age-Related Macular Degeneration. Clinical Medicine Insights: Therapeutics, 2013(), 81-93. https://doi.org/10.4137/CMT.S8921
- Wu, A. M., Wu, C. M., Young, B. K., Wu, D. J., Margo, C. E., & Greenberg, P. B. (2015). Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration. Journal of Ophthalmology, 2015(), 1-5-183. https://doi.org/10.1155/2015/710324