Title

Use of Furosemide to Clear Unusual Accumulation of 18F-FDG in a Kidney with Hypertrophic Junctional Renal Parenchyma

Translated Titles

使用利尿劑以排除氟-18-去氧葡萄糖正子造影時連結腎間質腎臟之異常尿液積留:個案報告

DOI

10.6332/ANMS.1903.012

Authors

吳家尚(Chia-Shang Wu);諶鴻遠(Daniel Hueng-Yuan Shen);黃文盛(Wen-Shen Huang);鄭澄意(Cheng-Yi Cheng);彭南靖(Nan-Jing Peng)

Key Words

連結腎間質 ; 氟-18-去氧葡萄糖正子造影 ; 利尿劑 ; junctional renal parenchyma ; FDG PET ; diuretics

PublicationName

核子醫學雜誌

Volume or Term/Year and Month of Publication

19卷3期(2006 / 09 / 01)

Page #

219 - 224

Content Language

英文

Chinese Abstract

一名49歲女性因間歇性膿尿及血尿,欲以氟-18-去氧葡萄糖之正子電腦斷層攝影確認是否有泌尿系統惡性病變。初步影像顯示右腎有異常之葡萄糖積聚,電腦斷層亦無法完全排除是否為尿液干擾。其後之延遲影像仍顯示相似結果。經投與利尿劑並重新造影,發現葡萄糖積聚完全消退故臆斷該疑似病灶為尿液積聚所致。該病患隨後接受超音波檢查、利尿腎圖及腎皮質攝影顯示右腎內一正常變異造成腎間質向腎內突出可能是導致影像異常之主因。

English Abstract

A 49-year-old female asked for cancer screening by positron emission tomography (PET) with 18F-fluo-rodeoxyglucose (FDG) due to usually right flank pain with intermittent pyuria and hematuria. 18F-FDG PET integrated with computed tomography (CT) was performed and showed a persistent FDG activity within right renal region on both initial (one hour post injection) and delay (two hours post injection as well as post-voiding) imaging. Intravenous administration of furosemide was employed to eliminate the retained urinary FDG activity. After the diuretic intervention the suspected FDG-avid lesion disappeared on the rescanning imaging. For further investigation of possible renal pathology, she received diuretic renogram, ultrasonography and (superscript 99m)Tc-dimercaptosuccinic acid renal cortical scan and it appeared that hypertrophy of junction parenchyma seemed to be the most likely etiology leading to FDG retention within renal calyx. From this anecdotal case we suggest that diuretic intervention can be a useful measure to elucidate unusual urinary retention in renal regions noticed on FDG PET.

Topic Category 醫藥衛生 > 基礎醫學
醫藥衛生 > 內科