Intussusception caused by appendiceal mucocele is extremely rare. Only few case reports were documented and most of those cases were female. We presented a 28 year-old male patient presented to our emergency department with intermittent epigastric and right lower abdominal pain for one week. Vomiting and bloody stool occurred one day prior to his arrival at our ED. Abdominal CT showed one appendiceal mass with intussusception, which was confirmed as an appendiceal mucocele with ileocecal intussusception in a laparotomy. The patient is free of illness for eleven months after operation.