Multidrug-resistant tuberculosis (MDR-TB), caused by the bacterium, Mycobacterium tuberculosis, is resistant to both isoniazid and rifampicin and is a phenomenon threatening to destabilize global tuberculosis control. Taiwan's Centers for Disease Control implemented a patient-centered DOTS (directly observed treatment, short-course)-Plus program for MDR-TB patients in May 2007. We report the case of a 71-year-old MDR-TB patient who successfully completed 18 months of MDR-TB treatment under the DOTS-Plus program, beginning October 2007. A third-generation (3G) mobile videophone was used to watch the patient take medicine throughout his course of treatment. His acceptance of the program and compliance with monitoring by videophone DOT (V-DOT) were excellent. We conclude that V-DOT can be an effective approach to case management for MDR-TB patients and can achieve a high level of adherence in selected cooperative cases in Taiwan.
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