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Primary Malignant Fibrous Histiocytoma of The Breast a Case Report and Review of The Literature

原發性乳房惡性纖維組織細胞瘤病例報告與文獻回顧

摘要


一個38歲的女性病人在其右側乳房發現有一10×4×8公分硬且固著的腫塊。病人在馬偕紀念醫院接受改良式根除性乳房切除術。病理報告顯示為惡性纖維組織細胞瘤。腫瘤在開刀後一年復發。病人於本科接受放射線治療,在右側胸壁、腋窩、鎖骨上凹窩、及下頸部,分別接受5040 cGy 的劑量。直到目前為止並未發現有此病存在的跡象。本文中分析從1964年到1992年所發表的35個乳房惡性纖維組織細胞瘤的病人,發現接受局部切除、簡單乳房切除或部份乳房切除的病人比接受根除性乳房切除的病人有較高的局部復發率。放射線治療對於只接受局部切除、簡單乳房切除或部份乳房切除的病人可能有助於局部疾病的控制。

並列摘要


Aim: Present a rare case of primary malignant fibrous histiocytoma of the breast and review the reported cases in the literature. Material and method: A 38 year-old female patient who ivitially complained of a l0×4×8 cm hard, fixed mass in her right breast underwent modified radical mastectomy at Mackay Memorial Hospital in May 1991. The pathology report revealed malignant fibrous histiocytoma. Tumor recurrence was noted one year later. Radiotherapy was administrated with a total dose of 5040 cGy to the right chest wall, axilla, supraclavicular fossa and lower neck. Result: No evidence of disease has been noted up to now (Sep. 1995). Discussion: Thirty five cases reported from 1964 to 1992 in article reviews show that the local recurrence rate is higher in patients who receive local excision, simple mastectomy or partial mastectomy than in those who receive radical mastectomy. If adequate surgery is not performed, radiotherapy can play a role of increasing local control for this disease.

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