SALVAGE CONCURRENT CHEMORADIATION THERAPY STABILIZES PROGRESSION OF RECURRENT INTIMAL SARCOMA OF THE LEFT ATRIUM: A CASE REPORT

以同步放化療治療復發左心房肉瘤：病例報告

呂隆昇(Long-Sheng Lu) ； 潘佳欣(Chia-Hsin Pan) ； 林永和(Yun-Ho Lin) ； 賴欣宜(Hsin-Yi Lai) ； 戴承正(Cheng-Jeng Tai) ； 許哲瑜(Che-Yu Hsu) ； 邱仲峯(Jeng-Fong Chiou) ； 丁禮莉(Lai-Lei Ting)

《放射治療與腫瘤學》 23卷4期 (2016/12) Pp. 277-284

https://doi.org/10.6316/TRO/201623(4)277

摘要

Intimal sarcoma is a rare primary malignancy of the heart. While surgery is the mainstay of curative treatment for newly diagnosed disease, the role of radiation for local recurrence remains elusive. Here we report a case with locally recurrent intimal sarcoma of the heart in the left atrium. Recurrence has been successfully stabilized with sandwich treatment. The patient survived for more than 48 months since the initial diagnosis and is still alive at the time of manuscript preparation. As intensity modulated radiation therapy is becoming widely accessible in Taiwan, there is an unmet need to document outcome and side effect profiles from aggressive CCRT to primary and recurrent cardiac malignancy.

關鍵字

Concurrent chemoradiation therapy (CCRT) ； Intimal sarcoma recurrence

並列摘要

內膜肉瘤是罕見的原發性心臟腫瘤。針對新診斷的內膜肉瘤，目前的標準治療為手術切除，而針對局部復發的內膜肉瘤，其最佳治療策略尚未有定論。本文報告一例左心房內膜肉瘤局部復發病例，患者在復發後併用化學治療與同步放化療而得到疾病控制，由初診斷迄今存活已達48 個月。強度調控放射治療在臺灣已相當普及，針對無法手術切除的心臟腫瘤，或可考慮以此技術配合化療積極進行局部治療。

並列關鍵字

同步放化療 ； 復發性內膜肉瘤