Translated Titles

Application of Proteomics in the Sports Science




王國慧(Kuo-Hui Wang);陳天文(Tien-Wen Chen)

Key Words

運動生理 ; 基因體 ; 分子生物學 ; 生物標記 ; exercise physiology ; genome ; molecular biology ; biomarker



Volume or Term/Year and Month of Publication

28卷1期(2014 / 03 / 01)

Page #

47 - 52

Content Language


Chinese Abstract


English Abstract

Proteomic is the expression of all proteins, which is mainly to research the properties of a wide range of proteomic and obtains a more comprehensive view from physiological pathways. In the application of sports sciences research, proteomics can also become more methods benefit and in basic or applied sports science, proteomics has unique expertise and technical capabilities that can help solve many scientific and health-related problems, it is recommended that the expertise and technology with the integration of sports science of proteomics, to explore the movement generated by a reaction with a variety of physiological adaptation, and lead exercise physiology to a more advanced level, as well as provide a reference of future sports science research.

Topic Category 社會科學 > 體育學
  1. Baldwin, K. M.(2000).Research in the exercise science: Where do we go from here?.Journal of Applied Physiology,88,332-336.
  2. Burniston, J. G.,Kenyani, J.,Wastling, J. M.,Burant, C. F.,Qi, N. R.,Koch, L. G.,Britton, S. L.(2011).Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity.Proteomics,11,3369-3379.
  3. Daniels, W. M.,Marais, L.,Stein, D. J.,Russell, V. A.(2011).Exercise normalizes altered expression of proteins in the ventral hippocampus of rats subjected to maternal separation.Experimental Physiology,97(2),239-247.
  4. de Moraes, R.,Valente, R. H.,León, I. R.,Trugilho, M. R. O.,Nóbrega, A. C. L.,Perales, J.,Tibiriçá, E.(2008).Chronic dynamic exercise increases apolipoprotein A-I expression in rabbit renal cortex as determined by proteomic technology.British Journal of Sports Medicine,42,386-388.
  5. Egan, B.,Dowling, P.,O'Connor, P. L.,Henry, M.,Meleady, P.,Zierath, J. R.,O'Gorman, D. J.(2011).2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time coursedependent remodelling in response to 14 consecutive days of endurance exercise training.Proteomics,11(8),1413-1428.
  6. Elrick, M. M.,Walgren, J. L.,Mitchell, M. D.,Thompson, D. C.(2006).Proteomics: Recent applications and new technologies.Basic and Clinical Pharmacology and Toxicology,98(5),432-441.
  7. Gandra, P. G.,Valente, R. H.,Perales, J.,Pacheco, A. G.,Macedo, D. V.(2012).Proteomic analysis of rat skeletal muscle submitted to one bout of incremental exercise.Scandinavian Journal of Medicine and Science in Sports,22,207-216.
  8. Guelfi, K. J.,Casey, T. M.,Giles, J. J.,Fournier, P. A.,Arthur, P. G.(2006).A proteomic analysis of the acute effects of high-intensity exercise on skeletal muscle proteins in fasted rats.Clinical and Experimental Pharmacology and Physiology,33,952-957.
  9. Hamilton, M. T.,Booth, F. W.(2000).Skeletal muscle adaptation to exercise: A century of progress.Journal of Applied Physiology,88,327-331.
  10. Hittel, D. S.,Hathout, Y.,Hoffman, E. P.(2007).Proteomics and systems biology in exercise and sport sciences research.Exercise and Sport Sciences Reviews,35(1),5-11.
  11. Hody, S.,Leprince, P.,Sergeant, K.,Renaut, J.,Croisier, J. L.,Wang, F.,Rogister, B.(2011).Human muscle proteome modifications after acute or repeated eccentric exercises.Medicine & Science in Sports & Exercise,43(12),2281-2296.
  12. Holloway, K. V.,O'Gorman, M.,Woods, P.,Morton, J. P.,Evans, L.,Cable, N. T.,Burniston, J. G.(2009).Proteomic investigation of changes in human vastus lateralis muscle in response to interval-exercise training.Proteomics,9(22),5155-5174.
  13. Leggate, M.,Carter, W. G.,Evans, M. J. C.,Vennard, R. A.,Sribala-Sundaram, S.,Nimmo, M. A.(2012).Determination of inflammatory and prominent proteomic changes in plasma and adipose tissue after high-intensity intermittent training in overweight and obese males.Journal of Applied Physiology,112(8),1353-1360.
  14. Martín-Sánchez, F. J.,Villalón, J. M.,Zamorano-León1, J. J.,Rosas, L. F.,Proietti1, R.,Mateos-Caceres, P. J.,López-Farré1, A. J.(2011).Functional status and inflammation after preseason training program in professional and recreational soccer players: A proteomic approach.Journal of Sports Science and Medicine,10,45-51.
  15. Norheim, F.,Raastad, T.,Thiede, B.,Rustan, A. C.,Drevon, C. A.,Haugen, F.(2011).Proteomic identification of secreted proteins from human skeletal muscle cells and expression in response to strength training.American Journal of Physiology - Endocrinology and Metabolism,301(5),E1013-1021.
  16. Ohlendieck, K.(2010).Proteomics of skeletal muscle glycolysis.Biochimica et Biophysica Acta,1804,2089-2101.
  17. Ohlendieck, K.(2011).Skeletal muscle proteomics: Current approaches, technical challenges and emerging techniques.Ohlendieck Skeletal Muscle,1(6),1-15.
  18. Pandey, A.,Mann, M.(2000).Proteomics to study genes and genomes.Nature,405,837-846.
  19. Petriz, B. A.,Gomes, C. P.,Rocha, L. A.,Rezende, T. M.,Franco, O. L.(2012).Proteomics applied to exercise physiology: A cutting-edge technology.Journal of Cellular Physiology,227(3),885-898.
  20. Rocha, L. A.,Petriz, B.,Borges, D. H.,Oliveira, R. J.,Andrade, R. V.,Domondt, G.,Franco, O. L.(2012).High molecular mass proteomics analyses of left ventricle from rats subjected to differential swimming training.BMC Physiology,12(1),11.
  21. Tipton, K. D.,Wolfe, R. R.(1998).Exercise-induced changes in protein metabolism.Acta Physiologica Scandinavica,162,377-387.
  22. Verrills, N. M.(2006).Clinical proteomics: Present and future prospects.Clinical Biochemist Reviews,27(2),99-116.
  23. Wilkins, M. R.,Pasquali, C.,Appel, R. D.,Ou, K.,Golaz, O.,Sanchez, J. C.,Hochstrasser, D. F.(1996).From proteins to proteomes: Large scale protein identification by two-dimensional electrophoresis and arnino acid analysis.Nature Biotechnology,14,61-65.
  24. 阮雪芬(2005)。蛋白質體學的介紹。化工,52(3),14-22。
  25. 周綠蘋(2005)。蛋白質體學之臨床與生物醫學之應用。臺灣醫學,9(5),628-636。
  26. 張裕旺、陳淑華、陳玉如(2005)。質譜技術於臨床蛋白質體學的應用。臺灣醫學,9(5),637-649。