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新生兒臟血CK正常值與DMD病人早期偵測的探討

Neonatal CK Value and Early Detection of Duchenne Muscular Dystrophy

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摘要


Early detection of patients or carrier of Duchenne muscular dystrophy with elevated CK is well documented in the literature. The purpose of this study is to find out normal CK value of cord blood during paripurm, in order to provide a diagnostic reference of DMD. Totally 327 newborn infants were evaluated for the cord blood CK value during paripurm. It revealed the mean CK value was 117.9±61.1IU/(ranged from 31.4to 455IU/1)the mean cord blood CK value of the male newborn was 125.1±69.8IU/1 and that of the female was 110.9±52.9IU/1. It showed a significant sex difference (P<0.05). There was no definite CK difference between the mode of dilivery, parity, birth weight or gestation period of the bady.

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並列摘要


Early detection of patients or carrier of Duchenne muscular dystrophy with elevated CK is well documented in the literature. The purpose of this study is to find out normal CK value of cord blood during paripurm, in order to provide a diagnostic reference of DMD. Totally 327 newborn infants were evaluated for the cord blood CK value during paripurm. It revealed the mean CK value was 117.9±61.1IU/(ranged from 31.4to 455IU/1)the mean cord blood CK value of the male newborn was 125.1±69.8IU/1 and that of the female was 110.9±52.9IU/1. It showed a significant sex difference (P<0.05). There was no definite CK difference between the mode of dilivery, parity, birth weight or gestation period of the bady.

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