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頸髓損傷後肺功能之追蹤

Pulmonary Function Following Cervical Cord Injury

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摘要


Traumatic cervical cord injury with quadriplegia generally causes respiratory dysfunction. A total of 50 cervical cord injured patients were collected for study of their pulmonary function. They were divided into two groups. Twenty-six cases with complete motor paralysis below lesion site (Frankel A or B) were placed in Group A, the other 24 cases with incomplete motor function (Frankel C or D) were placed in Group B. Pulmonary function test was done by using spirometer at 1 month, 6 months and 12 months following cervical cord injury. The pulmonary function was significantly worse in Group A than in Group B. Lesion level was found to be correlated with pulmonary function in Group A. The lower the injury cord, the better the pulmonary function. Furthermore, there was a significant difference in pulmonary function between lesion site above and below C5. The forced vital capacity (FVC), forced expiratory volume in 1st second (FEV1), peak expiratory flow (PEF) and mid maximal expiratory flow (MMEF) were around 33% of predicted normal value in patients with C6 or C7 lesion, but only around 25% of predicted normal value in those with C5 or above C5 lesion. In Group B, however, we failed to find any significant difference according to different lesion level. The effect of time on pulmonary function was ,determined by one way ANOVA. The FVC, FEV1, PEF and MMEF increased during the first year following cervical cord injury in both Group A and B. However, the improvement was shown statistically significant only during the first 6 months after injury. As for the amount of improvement attained during the time period studied, there was no significant difference between Group A and Group B.

並列摘要


Traumatic cervical cord injury with quadriplegia generally causes respiratory dysfunction. A total of 50 cervical cord injured patients were collected for study of their pulmonary function. They were divided into two groups. Twenty-six cases with complete motor paralysis below lesion site (Frankel A or B) were placed in Group A, the other 24 cases with incomplete motor function (Frankel C or D) were placed in Group B. Pulmonary function test was done by using spirometer at 1 month, 6 months and 12 months following cervical cord injury. The pulmonary function was significantly worse in Group A than in Group B. Lesion level was found to be correlated with pulmonary function in Group A. The lower the injury cord, the better the pulmonary function. Furthermore, there was a significant difference in pulmonary function between lesion site above and below C5. The forced vital capacity (FVC), forced expiratory volume in 1st second (FEV1), peak expiratory flow (PEF) and mid maximal expiratory flow (MMEF) were around 33% of predicted normal value in patients with C6 or C7 lesion, but only around 25% of predicted normal value in those with C5 or above C5 lesion. In Group B, however, we failed to find any significant difference according to different lesion level. The effect of time on pulmonary function was ,determined by one way ANOVA. The FVC, FEV1, PEF and MMEF increased during the first year following cervical cord injury in both Group A and B. However, the improvement was shown statistically significant only during the first 6 months after injury. As for the amount of improvement attained during the time period studied, there was no significant difference between Group A and Group B.

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