目的:本研究目的是在檢測臺灣版精神分裂症病人生活品質量表(LQOLP)之信、效度,並探討人口學特質、精神症狀、醫療環境與病人生活品質間的關係。方法:樣本來自北部某醫學中心精神科日間病房及門診之精神分裂症病人100名,進行量表信、效度之檢定,結果:本評量表各層面主觀生活品質Cronbach’s, a範圍0.53-0.82,再測信度ICC範圍0.60-0.92。本評量表與SF-36及LQOLP量表中三項綜合評量題目兩項效標工具間具有顯著相關,亦具有良好之建構效度。探索性因素分析發現六個因素(家庭關係、健康與安全、經濟、自主與安適、社交關係、休閒),病人主觀生活滿意度中,以家庭關係層面最佳,工作及經濟兩層面最差,研究發現情緒及負性症狀、醫療環境、婚姻狀況為分居者、年齡20-30歲,是影響病人主觀生活品質之重要預測因子。結論:研究結果有助於瞭解病人多層面主、客觀生活品質,可用為精神衛生政策擬定之參考,有利於精神分裂症病人生活品質之本土性資料建立,以為未來跨文化比較研究之基礎。
The purpose of this study was to develop and test the reliability and validity of the Taiwanese version of Lancashire Quality of Life Profile(T-LQOLP). The relationship between demographic factors, psychotic symptoms, care settings, and quality of life (QOL) of patients with schizophrenia were also be examined. Methods: One hundred patients with schizophrenia were recruited from patients who were receiving hospital day care or were treated in an outpatient setting of a university hospital in Taipei. Data were collected by personal interview after written informed consent was obtained. Results: The T-LQOLP was established after linguistic modification. The internal consistency (Cronbach’s a) ranged from 0.53 to 0.82 for the nine subjective QOL domains. The test-retest reliability ICCs ranged from 0.60 to 0.92 in the nine subjective QOL domains. The SF-36 and three items from the T-LQOLP were used as the criterion-related validity tools. The T-LQOLP had significant correlations between the two scales, and had satisfactory contruct validity. Exploratory factor analyses revealed a six-factor (family relations, health and safety, finance, autonomy and well-being, social relations, and leisure) model. Among the nine subjective QOL domains, the highest satisfaction domain was family relations, while the lowest satisfaction domains were work and finance. The best factors in predicting subjective QOL were affect symptoms, care setting, separate marital status, age range of 20-3 0 years, and negative symptoms. Conclusions: This study has successfully established the T-LQOLP by demonstrating its satisfactory reliability and validity. This instrument is applicable for use in Taiwanese patients with schizophrenia. The T-LQOLP can also be served as a rating scale for cross-cultural study and as a tool for clinical psychiatric assessment in Taiwan. (Full text in Chinese)