以動物實驗探討經陽極表面處理微型骨釘之施力時機與穩固度評估

The Evaluaiotn of Loading Timing and Stability of Anodized Mini-Screw in Animal Study

高俊義(Chun-Yi Kao) ； 鄭信忠(Hsin-Chung Cheng) ； 蔡吉陽(Chi-Yang Tsai)

《中華民國齒顎矯正學雜誌》 18卷2期 (2006/06) Pp. 5-11

https://doi.org/10.30036/TJO.200606.0002

摘要

陽極處理技術可以有效增加鈦金屬植體表面氧化膜厚度與多孔性，有利於細胞貼覆及組識生長，增進骨組識生長的質與量，而有助於縮短骨整合所需的時間。本研究之目的在以體內試驗評估微型陽極處理骨釘(mini-screw)，經不同癒合時間施力，觀察其穩固度，尋找最利於骨釘施力的時機。試驗採用尺寸分別為1.3mm之微型骨釘36支，實驗對象為三隻雄性小獵犬(beagle)，植入位置為下顎無牙區處，施力前之等待癒合時間為0週、2週與6週三組，再以鎳鈦合金彈簧連接同組骨釘，控制施力約為200克，持續三個月，於動物犧牲後，以組識切片測量骨釘與骨接觸程度。結果顯示，骨釘成功率為87.5%，骨接觸程度分別為37.57%（癒合0週）、78.52%（癒合2週）與47.73%（癒合6週），高於先前文獻研究結果，陽極處理效果可能是影響的主因，同時等待癒合時機2週顯示有最佳結果，與文獻研究結果類似。

關鍵字

矯正 ； 錨定 ； 微型骨釘 ； 陽極表面處理

並列摘要

[Objective] The porous oxide surface characterier of tianium alloy can be improved by the technology of anodization which benefits cell adhesion and tissue growth. It also accelerates the quality and quantity of bone growth that n terms helps to shorten the period of bone healing. The purpose of this study was to evaluate the effects of anodized mini-screws on the stability n vivo. [Materials and Methods] The chosen sizes of the mini-screws were 1.3mm. We used 12 each on three male beagle dogs. We selected edentulous areas for implantation and the time of healing before applying force were 0 week, 2 weeks, and 6 weeks respectively. Then we connected NiTi coil springs to the mini-screws n the same group and the magnitude of force was controlled at 200g. The histology was examined to measure bone-implant contact (BIC). [Results and Discussion] The results showed that the success rates were 87.5%. BIC of the former group were 37.57% (healing time 0 week), 78.52% healing time 2 weeks), and 47.73% (healing time 6 weeks) respectively. These were all higher than previous studies. [Conclusion] In the future development, we are hoping to combine this technology of anodization to shorten the length of mini-screws for clinical use in order to improve their safety and stability.

並列關鍵字

orthodontics ； anchorage ； mini-screw ； anolized