Acute Pulmonary Edema Following Ingestion of an Antiseptic Solution Containing Naphazoline: A Case Report

口服抗菌藥水（白藥水）後引發急性肺水腫：病例報告

林坤辰(Kung-Chen Lin) ； 邱垂祥(Chui-Hsiang Chiu)

《Journal of Emergency Medicine, Taiwan》 13卷1期 (2011/03) Pp. 16-20

摘要

我們在此報告一位八十歲女性患者，故意喝下白藥水，隨後引發高血壓、急性肺水腫以及呼吸衰竭，並且導致插管。在住院第四天胸部X光顯示肺水腫已經緩解，隨後成功拔除氣管內管。這個抗菌藥水包含荼甲唑咻(naphazoline)這種成份，它是imidazoline的衍生物並且具有alpha腎上腺素的作用，我們推論荼甲日坐日林會引起密集的血管收縮，因此造成高血壓以及肺水腫。總之，我們呈獻一個少見的中毒病例，並且想要提醒急診醫師：急性肺水腫可以經由毋需處方謹的藥物來引發。

關鍵字

急性肺水腫 ； 急救用抗菌藥水 ； 荼甲唑啉

並列摘要

We report an 80-year-old woman who intentionally drank an antiseptic solution, with subsequent hypertension, acute pulmonary edema and respiratory failure requiring intubation. On the fourth hospital day, chest radiography showed resolution of pulmonary edema and she was extubated successfully. This antiseptic solution contained naphazoline, an imidazoline derivative with alpha adrenergic effects. We speculate that naphazoline induces intense vasoconstriction and thereby causes hypertension and pulmonary edema. In summary, we present a case of a rare toxicity and would like to remind emergency physicians that acute pulmonary edema can be caused by over-the-counter drugs.

並列關鍵字

acute pulmonary edema ； antiseptic solution ； naphazoline