Translated Titles

Critical Illness Polyneuropathy and Myopathy


汪子瑄(Tze-Hsuan Wang);吳英黛(Ying-Tai Wu)

Key Words

重症多神經病變 ; 重症肌肉病變 ; 物理治療 ; Critical illness polyneuropathy ; Critical illness myopathy ; Physical therapy



Volume or Term/Year and Month of Publication

31卷1期(2006 / 02 / 01)

Page #

46 - 54

Content Language


Chinese Abstract


English Abstract

Critical illness polyneuropathy and myopathy refers to severe muscle weakness and atrophy in patients with critical illness, such as sepsis or multiple organ failure. The problem often impaired patients' limb movement and function, prolonged their ventilator dependence, and increased the length of stay in intensive care unit and hospital and in-hospital mortality. It was different from the weakness from prolonged immobility and might persist in long-term survivors that limited their body function, activity, and social participation. Critical illness polyneuropathy (CIP) causes acute axonal injury in peripheral nerves and muscle denervation. The reported incidence of CIP varied from 22% to 82%. To diagnose critical illness myopathy (CIM) requires muscle biopsy. The incidence of CIM was similar to CIP in critical patients and CIM may coexist with CIP. The purpose of this review was to describe the clinical manifestations, diagnostic methods, pathogenesis, prevention, treatment, and prognosis of CIP and CIM. We concluded that physical therapists should be aware of the problems associated with critical illness polyneuropathy and myopathy, notify the existence to other team members, make the treatment plan to assist patients weaning from ventilator, promote their recovery of body function, and follow up their long-term activity level and social participation.

Topic Category 醫藥衛生 > 醫藥總論