- 期刊
Microcirculatory Complexity Responses to the Application of Skin-Surface-Contacting Pressure Stimulation around Normal Blood Pressure
並列摘要
This study discriminates the microcirculatory responses to the application of pressure stimulation (PS) using approximate entropy (ApEn) analysis to characterize the temporal fluctuations within beat-to-beat laser Doppler signals, Experiments were performed with a control group in which PSs were not applied and with five groups in which PSs of 20, 60, 100, and 160 mmHg were applied, respectively. Each experiment involved making a 20-minute baseline recording and then recording effect data 0-20 minutes (M1) and 50-70 minutes (M2) after stopping skin-surface PS, ApEn and wavelet analyses were performed on the assessed laser Doppler signals. At the pressed site, a significant microcirculatory blood flow (MBF) increase was observed that persisted to M2 only in the 60-mmHg PS group (PS60), The only significant increase in ApEn also occurred in PS60, and the only significant decrease in ApEn occurred in the 100-mmHg PS group, Changes in ApEn can help the identification of the range of PSs that can induce longer-persisting improvements in the MBF, These changes in MBF parameters and ApEn can be attributed to different levels of the pressure-induced vasodilation response, The present findings may aid attempts to improve the local MBF and prevent the occurrence of pressure-associated lesions.