Title

矫治力作用下大鼠牙髓组织中MEK的变化

Translated Titles

Effects of Orthodontic Force on MEK in Rat Pulpal Tissue

Authors

潘乙怀(Yi-Huai Pan);刘传通(Chuan-Tong Liu);王惠宁(Hui-Nin Wang)

Key Words

牙髓 ; 甲硫氨酸脑啡肽MEK ; 矫治力 ; Dental pulp ; Met-enkephalin ; Orthodontic force

PublicationName

口腔醫學研究

Volume or Term/Year and Month of Publication

21卷1期(2005 / 02 / 28)

Page #

45 - 46

Content Language

簡體中文

Chinese Abstract

目的:探讨矫治力对大鼠牙髓组织中MEK的影响。方法:1)对大鼠切牙分别施以100g、200g、300g的矫治力,24h后测定MEK的含量。2)对大鼠切牙施以100g的矫治力,分别于施力后1h、24h、48h、72h测定MEK的含量结果:与对照组相比,牙髓组织中MEK含量1)于施加矫治力后显著降低,目与矫治力具有负相关;2)在施力后24h、48h有显著性降低,72h后向正常水平恢复。结论:矫治力启动了大鼠牙髓组织中与疼痛相关的神经肽的代谢途径。

English Abstract

Objective: To study the effects of orthodontic force on MEK in rat pulpal tissue. Methods: 1) The contents of MEK was measured after supplying orthodontic force of 100g, 200g, 300g to incisor of rat respectively for 24h. 2) The contents of MEK was measured at the end of 1h, 6h, 24h and 72h after supplying orthodontic force of 100g to incisor of rat. Results: 1) MEK concentrations decreased significantly caused by orthodontic force in the experimental teeth compared with controls, and had a statistically significant inverse correlation to the amount of applied force. 2) The contents of MEK decreased significantly at the coil of 24h, 48h, and returned to nomal at 72h after the orthodontic force was supplied. Conclusion: Orthodontic force mobilizes neuropeptidergie pathway in the rat tooth pulp.

Topic Category 醫藥衛生 > 牙科與口腔科