Inaccurately blood sampling conducted by nursing staff is the main influence on blood specimen quality. Redrawing blood specimen may delay therapy and endangers patient safety significantly. The accuracy in blood sampling was only 50.7% from January 7(superscript th) to 13(superscript th), 2008, due to: lack of blood drawing techniques and insufficient training in blood sampling, deficient knowledge on choosing sampling devices, patient body malorientation, scanty subsidiary instruments for blood specimens handling and lack of portable specimen containers. From January 28(superscript th) to May 7(superscript th). 2008, we created and started regulating blood drawing standards, making teaching demonstration videos, arranging on-the-job training and designing adjunct tools for blood sampling. These improvements increased the blood sampling accuracy rate from 50.7% to 98.2%. The project successfully improved patient safety and nursing care quality.