Four known triterpenoids (lupeol, lupenone, squalene, cycloartenol) and two phenolic compounds were isolated from Ampelopsis brevipedunculata var. ciliate (Nakai) Lu. of the Ophthalmic Folk Medicines in Taiwan. According to the literature, lupeol and squalene can enhance Retinal Pigment Epithelial (RPE) cell phagocytosis in retina. Structure determination was carried out by spectral techniques such as, EI-MS, IR, 1H-NMR and 13C-NMR.