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補充孕烯醇酮對增強式運動後排球選手肌肉損傷的影響

The Effect of Pregnenolone Supplement on Muscle Damage after Plyometric Training for Volleyball Players

摘要


Plyometric training, usually served as one drill to enhance bouncing ability of volleyball players, would cause more muscle damage. Pregnenolone was one precursor of sex steroid hormone. This study was to investigate the effect of oral pregnenolone after plyometric training on serum DHEA-S, testosterone, cholesterol, and muscle damage. Ten male professional volleyball players were randomized to the control and experimental groups. Following single plyometric training, the control group was given placebo intake and the experimental group was oral pregnenolone for one week during which fasting blood sample every morning was collected to analyze DHEA-S, testosterone, cholesterol and CK. After two weeks, two groups crossover with the same procedure. The results found that CK AUC was lower in the experimental group than the control group (the control group: 1097.23±308.92>the experimental group: 346.78±175.06). However, no significant changes were noted in serum DHEA-S, testosterone and cholesterol. The result denoted that oral pregnenolone effectively reduced muscle damage from plyometric training with no effect on DHEA-S and testosterone, which suggested that pregnenolone is capable to diminish muscle damage from high-intensity training without controversial issues of illicit drug.

並列摘要


Plyometric training, usually served as one drill to enhance bouncing ability of volleyball players, would cause more muscle damage. Pregnenolone was one precursor of sex steroid hormone. This study was to investigate the effect of oral pregnenolone after plyometric training on serum DHEA-S, testosterone, cholesterol, and muscle damage. Ten male professional volleyball players were randomized to the control and experimental groups. Following single plyometric training, the control group was given placebo intake and the experimental group was oral pregnenolone for one week during which fasting blood sample every morning was collected to analyze DHEA-S, testosterone, cholesterol and CK. After two weeks, two groups crossover with the same procedure. The results found that CK AUC was lower in the experimental group than the control group (the control group: 1097.23±308.92>the experimental group: 346.78±175.06). However, no significant changes were noted in serum DHEA-S, testosterone and cholesterol. The result denoted that oral pregnenolone effectively reduced muscle damage from plyometric training with no effect on DHEA-S and testosterone, which suggested that pregnenolone is capable to diminish muscle damage from high-intensity training without controversial issues of illicit drug.

並列關鍵字

pregnenolone DHEA-S testosterone CK muscle damage

參考文獻


Yang, S. C.,Chen, C. Y.,Liao, Y. H.,Lin, F. C.,Lee, W. C.,Cho, Y. M.(2005).Interactive effect of an acute bout of resistance exercise and dehydroepiandrosterone administration on glucose tolerance and serum lipids in middle-aged women.The Chinese Journal of Physiology.48(1),23-29.
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Brodsky, I. G.,Balagopal, P.,Nair, K. S.(1996).Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men a clinical research center study.Journal of Clinical Endocrinology & Metabolism.81(10),3469-3475.
Brown, G. A.,Vukovich, M. D.,Sharp, R. L.,Reifenrath, T. A.,Parsons, K. A.,King, D. S.(1999).Effect of oral DHEA on serum testosterone and adaptations to resistance training in young men.Journal of Applied Physiology.87(6),2274-2283.
Chen, Y.-W.,Hubal, M. J.,Hoffman, E. P.,Thompson, P. D.,Clarkson, P. M.(2003).Molecular responses of human muscle to eccentric exercise.Journal of Applied Physiology.95(6),2485-2494.

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