Error is one of human nature, so the word ”Safety” usually proven its importance by the blood and lives. In this paper, as of the start of human error, described five types of error, the three defense lines of error management , the five management principles, and that managers need to understand the concept of ”as long as people may make mistake,”. Abandon the old way of error penalties, to accept the Error Management and became the Errors detector and the one who make the correction. Error management can eliminating the human factor and enhances a personal capacity and system functionality.