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中藥改善藥癮替代療法(美沙冬)之療效

Traditional Chinese medication Improves Efficacy of Methadone Maintenance Treatment

摘要


使用毒品會影響病患的身心功能,罹患各種疾病,需要社會提供醫療資源介入協助。海洛因成癮替代療法的第一線藥物為美沙冬,但其類似鴉片類的戒斷症狀,須持續數週的時間,且在戒斷期可能出現精神症狀與生活品質下降。此研究計畫擬透過回溯性資料,來分析臺北市立聯合醫院林森中醫昆明院區(以下簡稱本院區)接受美沙冬替代療法的藥癮者,比較接受不同中藥治療次數的族群,觀察並評估藥癮者美沙冬服用量與出席率。結果中藥治療達6次以上之藥癮患者,在美沙冬平均使用量、平均變化量與出席率的表現,確實與中藥治療低於6次的藥癮者有顯著差異,中藥治療有利於藥癮者減少對美沙冬的依賴性。

並列摘要


Drug addicts have a negative effect on their physical and mental function, suffer from various diseases and need more medical resources. First line therapy for heroin addiction is Methadone Maintenance Treatment (MMT). After the last dose, heroin (Opiate) withdrawal symptoms experience for a week. However, methadone (Opiate-like) withdrawal symptoms last for several weeks and may be a risk of mental illness and a decline in quality of life. This retrospective study in the Department of Chinese Medicine, Taipei City Hospital, Linsen Chinese Medicine and Kunming Branch analyzes a group of heroin addicts in an intervention of methadone maintenance treatment coupled with traditional chinese medication to evaluate the therapeutic effectiveness of tradional chinese medication on beliefs about drug abuse and life adjustment. Based on the results of this study, the average drug use, average decrease, and attendance rate of Methadone in patients with drug addiction that has been treated for more than 6 times in traditional Chinese medicine are indeed significantly different from those in drug addicts who have been treated for less than six times. Chinese medicine treatment is beneficial for drug addicts to reduce dependence on Methadone.

參考文獻


虞凱強、許中華(2017)。探討中醫在海洛因戒毒中扮演的角色。中醫內科醫學雜誌。15(1)
(2000).Methadone Guidelines Prescribers and Pharmacists.Victoria, Australia:Department of Human Services, Drugs and Poisons Unit.
(2007)。美沙冬替代療法治療指引。台北:衛生署疾病管=Centers for disease control。
Booth, RE,Corsi, KF,Mikulich-Gilbertson, SK(2004).Factors associated with methadone maintenance treatment retention among street-recruited injection drug users.Drug Alcohol Depend.74,177-85.
Darke, S.,Swift, W.,Hall, W.(1994).Prevalence, severity and correlates of psychological morbidity among methadone maintenance clients.Addiction.89,211-217.

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